短暂性脑缺血对继发脑梗死的影响及危险因素

Effect of transient ischemic attack on secondary cerebral infarction and its related risk factors

目的:探究短暂性脑缺血发作(TIA)对继发脑梗死的影响及其相关危险因素,从而帮助TIA患者降低继发脑梗死的发病率,并为疾病的治疗康复提供建议。方法:选取2015-01~12我院收治的TIA患者132例,根据是否发展为继发脑梗死,分为对照组和观察组,对照组78例,均未发展为继发脑梗死;观察组54例,均发展为继发脑梗死。比较两组的一般资料,并对影响TIA发展为继发脑梗死的相关危险因素进行分析。结果:观察组首次发作至治疗的时间、血压、血糖以及胆固醇等水平均显著高于对照组,差异具有统计学意义(P<0.05)。同时,观察组患者年龄≥70岁、有高血压、糖尿病以及冠心病病史的患者数也明显多于对照组,差异具有统计学意义(P<0.05)。经多元Logistic分析显示,年龄、高血压以及糖尿病病史是影响TIA患者发展为继发脑梗死的相关危险因素。结论:影响TIA患者发展为继发脑梗死的相关危险因素有年龄、高血压以及糖尿病病史,临床医务人员应予以关注。

Objective：To explore the transient ischemic attack（TIA）for secondary cerebral infarction and its related risk factors to help reduce the incidence of patients with TIA and cerebral infarction,and provide guidance for the treatment and rehabilitation of diseases.Methods：A total of 132 patients with TIA were selected in January to December 2015,and divided into control group and observation group depending on whether the patient can become secondary to cerebral infarction.78 patients in the control group were not to become secondary to cerebral infarction,and 54 patients in the observation group,were to become secondary to cerebral infarction.General information on two groups were compared,and the impact of TIA become risk factors and cerebral infarction were analyzed.Results：The patients from the first episode of treatment time,blood pressure,blood sugar and cholesterol levels were to be significantly higher,the difference was statistically significant（P〈0.05）.At the same time,the observation group patients aged ≥70 years,history of hypertension,history of coronary heart disease and the number of diabetic patients have a history of significantly more than the control group,the difference was statistically significant（P〈0.05）,by multivariate Logistic regression analysis showed that age,hypertension and diabetes in patients with a history of TIA affecting the development of the related risk factors become secondary to cerebral infarction.Conclusion：TIA patients become secondary to cerebral infarction risk factors are age,history of hypertension and diabetes,clinicians should be concerned.