并发表皮囊肿的瘢痕疙瘩75例临床分析

Clinical analysis of 75 cases of keloid with epidermal cyst

目的:提高对并发表皮囊肿的瘢痕疙瘩的临床认识,为改进其治疗方法提供依据。方法:回顾性分析75例并发表皮囊肿的瘢痕疙瘩患者的临床特点、组织病理表现、治疗及随访情况。结果:该病患者以中、老年人多见,病史均较长,好发于胸部、腹部、背部及外生殖器。主要表现为瘢痕疙瘩反复破溃、流脓。其中41例患者术中可见表皮囊肿结构。皮损组织病理检查示有完整表皮囊肿结构者62例,可见表皮囊肿炎症反应者37例。常规治疗同时彻底清除表皮囊肿,随访2~5年均未复发。结论:临床上病史较长,有反复破溃流脓的中、老年瘢痕疙瘩患者更易并发表皮囊肿。治疗中彻底清除表皮囊肿可减少其破溃。

Objective： To improve the knowledge of keloid with epidermal cyst, providing the basis for improving its treatment. Methods： Seventy-five cases were retrospectively analyzed in respect to the clinical manifestations, pathological examination, therapy and the follow-up. Results： Most of patients were middle age to aged with a long history of disease. The skin lesions occurred commonly on the chest, abdomen, back and external genitalia. The main clinical manifestations included repeatedly bursting and purulent discharge of keloid. Epidermal cyst structure could be seen in 41 cases. Histopathological examination showed a complete epidermal cyst structure in 62 cases, and inflammation of epidermal cyst in 37 cases. During 2 to 5-year follow-up, no relapse occurred following conventional treatment plus complete removal of epidermal cyst. Conclusion： Clinically, the middle age to aged patients with a long histoly of disease and repeated ulceration of keloid are more likely to be complicated with epidermal cyst. Thorough removal of epidermal cyst can reduce the bursting of keloid.