期刊文献+

西药结合健脾化浊汤治疗H型高血压128例分析 被引量:1

The Analysis of 128 cases of H type hypertension treated with western medicine combined with Spleen-Hua turbid Decoction
下载PDF
导出
摘要 目的:探究西药结合健脾化浊汤治疗H型高血压的疗效。方法:选H型高血压患者128例,均分为观察组和对照组。对照组服用西药治疗,观察组加服健脾化浊汤。记录降压有效率、血浆Hcy水平。结果:治疗后,观察组总有效率为84.38%,明显高于对照组的67.19%(P<0.05)。治疗前、治疗4周、停药4周时患者血浆中Hcy水平分别为(22.59±2.43)μmol/L、(13.41±1.50)μmol/L、(8.45±1.37)μmol/L,对照组对应数据为:(22.87±2.38)μmol/L、(14.81±2.02)μmol/L、(13.94±3.11)μmol/L。可见,治疗4周后两组Hcy水平均较治疗前有所降低,有显著差异(P<0.05),两组间无显著差异(P>0.05),停药4周后,观察组Hcy水平显著低于对照组,差异有统计学意义(P<0.05)。结论:西药结合健脾化浊汤治疗H型高血压降压效果显著,停药后Hcy下降显著稳定,值得临床推广。 Objective: To explore the curative effect of Jianpi Huazhuo decoction combined with western medicine treatment of H type hypertension. Methods: 128 cases of type H patients with hypertension were divided into observation group and control group. The control group was given western medicine treatment, the observation group with oral Jianpi Huazhuo decoction. Record the antihypertensive efficiency, treatment of the plasma Hey level. Results :The results showed that after treatment, the total efficiency of the observation group was 84.38%, 67.19% higher than the control group (P 〈 0.05 ). Before treatment, 4 weeks of treatment, stopping at 4 weeks in the plasma of patients with Hey were: (22.59±2.43)μ mol/L,( 13.41±1.50)μmol/L (8.45±1.37)μmol/L, the corresponding data for the control group: (22.87±2.38)μ mol/L, ( 14.81±2.02)μmol/L, ( 13.94±3.11 )μmol/L, visible, Hcy level of two groups of patients after 4 weeks of treatment were lower than before treatment, there were significant differences (P 〈 0.05), no statistics between the two groups Learning differences (P 〉 0.05 ), after 4 weeks of withdrawal, the Hcy level of the observation group was significantly lower than that of the control group, the difference was statistically significant (P 〈 0.05).conclusion. Western medicine. The effect of H type hypertension antihypertensive treatment was significant, Hcy decreased significantly after withdrawal, it is worthy of clinical application.
作者 许家艳
出处 《北方药学》 2017年第4期22-23,共2页 Journal of North Pharmacy
关键词 西药 健脾化浊汤 H型高血压 HCY Western medicine Invigorating spleen and reducing turbid Decoction Hcy
  • 相关文献

参考文献5

二级参考文献43

  • 1李立明,饶克勤,孔灵芝,姚崇华,向红丁,翟凤英,马冠生,杨晓光,中国居民营养与健康状况调查技术执行组.中国居民2002年营养与健康状况调查[J].中华流行病学杂志,2005,26(7):478-484. 被引量:1780
  • 2裴玉琨,周围血管病学[M].北京:北京科学技术出版社,1995:189.
  • 3陈灏珠.实用内科学[M]12版.北京:人民卫生出版社,20061526.
  • 4Kang SS,Wong PW,Malinow MR. Hyper homocysteinemia as a risk factor for occlusive vascular disease[J].Ann Kev Nutri,1992.279-298.
  • 5郑筱萸.中药新药临床研究指导原则(试行)[S]{H}北京:中国医药科技出版社,200274-76.
  • 6裴玉琨.周围血管病学[M]{H}北京:北京科学技术出版社,1995189.
  • 7李建平,霍勇,刘平,秦献辉,关德明,葛均波,胡健,王燕妮,张馥敏,毛广运,徐希平.马来酸依那普利叶酸片降压、降同型半胱氨酸的疗效和安全性[J].北京大学学报(医学版),2007,39(6):614-618. 被引量:386
  • 8Pezzini A,Zotto ED, Padovani A.Homocysteine and cerebralischemia:pathogenic and therapeutical implications [J].Curr Me dChem, 2007,14(3):249-263.
  • 9Li Z,Sun L,Zhang H,et a/.Elevated plasma homocysteine wasassociated with hemorrhagic and ischemic stroke ,bulmethylenetelrahydrofolate reductase gene C677 T polymorphismwas a risk factor for thrombotic stroke:a Multicenter Case-ControlStudy in China[J].5zroAe, 2003,34( 9): 2085-2890.
  • 10Homocysteine Lowering TrialistsJ Collaboration.Dese -dependenteffects of folie acid on blood concentrations of homacysteine : ameta-analysis of the raldomized-als [J]Am J Clin 2005,82(4):806-812.

共引文献51

同被引文献42

引证文献1

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部