探讨利培酮对精神分裂症合并糖尿病患者的疗效及认知功能的影响

Objective the Effect of Risperidone on Schizophrenia Patients With Diabetes Mellitus

目的研究分析精神分裂症合并糖尿病患者接受利培酮治疗后的治疗效果和认知功能改善情况。方法我院对76例精神分裂症合并糖尿病患者进行了研究分析,分成对照组和观察组,均有38例,对照组使用常规治疗,观察组使用常规治疗和利培酮口服治疗,经过8周治疗,对比分析两组的临床效果和认知功能改善情况。结果经过治疗,观察组患者的临床治疗有效率是97.37%,比对照组患者的73.68%高,结果差异存在统计学意义(P<0.05)。治疗前两组的WAIS-RC评分差异无统计学意义,经过8周治疗,观察组的评分平均是(91.6±12.4)分、对照组是(82.5±13.7)分,结果差异存在统计学意义(P<0.05)。结论利培酮对精神分裂症合并糖尿病患者的临床治疗效果具有促进作用,能够改善患者的认知功能,促进患者的恢复。

Objective To study the treatment effect and cognitive function of schizophrenia patients with diabetes mellitus after risperidone treatment. Methods 76 cases of patients with diabetes mellitus in our hospital were analyzed and divided into control group and observation group, 38 cases in each group, the control group using conventional treatment, the observation group used routine treatment and oral risperidone treatment, after 8 weeks of treatment, compared the clinical effect and cognitive function in two groups improved the situation. Results After treatment, the clinical efficacy of the observation group was 97.37%, which was higher than that of the control group, and the difference was statistically significant（P〈0.05）. Two groups before treatment WAIS-RC score no significant difference, after 8 weeks of treatment, the observation group the average score was（91.6±12.4） points, the control group was（82.5±13.7）. There were significant differences（P〈0.05）. Conclusion Risperidone can improve the clinical treatment effect of schizophrenia patients with diabetes mellitus, improve the cognitive function of patients and promote the recovery of patients.