间歇性高容量血液滤过治疗烧伤脓毒症的临床疗效分析

Clinical Analysis of Intermittent High Volume Hemofiltration in the Treatment of Burn Sepsis

目的分析间歇性高容量血液滤过治疗烧伤脓毒症的临床疗效。方法分析选取我院收治的85例烧伤脓毒症患者的资料,依据治疗方案的不同将其分为2组,对照组(41例)行常规治疗,观察组(44例)行PHVHF治疗,对比两组疗效性指标。结果治疗后,观察组APACHEⅡ评分(13.16±2.75)分,心率(94.36±11.25)次/min,IL-6(62.13±20.14)pg/ml,TNF-α(21.53±15.21)pg/ml,对照组分别为(18.23±3.10)分、(98.20±13.20)次/min、(83.12±20.14)pg/ml、(33.45±18.89)pg/ml,观察组各指标水平均优于对照组,比较差异均具有统计学意义(P<0.05)。结论烧伤脓毒症予PHVHF治疗,可改善患者血流动力学指标与病情,且有效清除炎性介质。

Objective To analyze the clinical efficacy of intermittent high volume hemofiltration in the treatment of burn sepsis. Methods The data of 85 patients with burned sepsis were divided into two groups according to the different treatment regimen. The control group （41 cases） underwent routine treatment. The observation group （44 cases） was treated with PHVHF, and the curative effect indexes were compared. Results After treatment, the APACHE Ⅱ score was （13.16±2.75）points, heart rate was （94.36±11.25） times/rain, IL-6 was （62.13±20.14）pg/ml, TNF-α was （21.53±15.21） pg/ ml in observation group. And the control group was （18.23±3.10） points, （98.20±13.20） times/rain, （83.12±20.14）pg/ml, （33.45±18.89） pg/ml, the observation group were better than the control group, the difference was statistically significant （P 〈 0.05）. Conclusion Burned sepsis to PHVHF treatment, can improve the patient＇s hemodynamie parameters and disease, and effective removal of inflammatory mediators.