显微镜下经鼻蝶窦垂体瘤切除术的临床疗效观察

Clinical Observation on Transsphenoidal Sinus Pituitary Resection Under Microscope

目的探讨显微镜下经鼻蝶窦垂体瘤切除术的临床疗效。方法选取2016年1—12月内蒙古省赤峰市医院收治的112例脑垂体瘤患者作为研究对象,所有患者均采用显微镜下经鼻蝶窦垂体瘤切除术治疗,回顾性分析患者的临床资料。结果所有患者均顺利完成手术,手术后无视神经损伤、颅内感染、死亡病例。泌乳素腺瘤患者术后血清泌乳素水平、长激素瘤患者术后血清生长激素水平均显著低于手术前,均P<0.05。结论显微镜下经鼻蝶窦垂体瘤切除术是一种安全、可靠的手术方式。

Objective To investigate the clinical curative effect of transsphenoidal sinus pituitary resection under microscope. Methods From January to December 2016, 112 cases of pituitary adenoma were selected from Chifeng hospital of Inner Mongolia as the research object, all patients were treated by microscopic transsphenoidal pituitary tumor resection, the clinical data were retrospectively analyzed. Results All patients were successfully completed operation, after surgery without optic nerve injury, intracranial infection, death cases. The serum levels of prolactin in patients with prolaetinoma were significantly lower than those before operation （P 〈 0.05）. Conclusion Transsphenoidal sinus pituitary resection is a safe and reliable surgical method.