降钙素原检测对新生儿败血症早期诊断治疗及病情评估的临床意义

Clinical Significance of Procalcitonin in Early Diagnosis and Treatment of Neonatal Septicemia

目的对降钙素原检测对新生儿败血症早期诊断治疗及病情评估的临床意义进行分析。方法选择2015年1月-2016年12月新生儿败血症患儿200例为研究对象,作为研究组,选择同期200例非新生儿败血症患儿作为对照组,检测两组的降钙素原水平,评价降钙素原检测对新生儿败血症早期诊断治疗及病情评估的临床意义。结果研究组治疗前降钙素原水平高于对照组,差异有统计学意义(P<0.05);经治疗后,研究组患儿降钙素原水平显著降低,跟治疗前比较差异有统计学意义(P<0.05);研究组治疗后降钙素原水平和对照组差异无统计学意义(P>0.05)。结论降钙素原检测对新生儿败血症早期诊断治疗及病情评估的效果确切,可及早为新生儿败血症作出诊断,并及时采取有效治疗措施,改善新生儿预后,值得推广。

Objective To analyze the clinical significance of procalcitonin in early diagnosis and treatment of neonatal septicemia. Methods 200 cases with neonatal septicemia from January 2015 - December 2016 were selected as the study group, and 200 cases with neonatal sepsis were selected as control group. Two groups were detected the procalcitonin level, and the clinical significance of procalcitonin detection in evaluation of early diagnosis and treatment of neonatal sepsis and disease were analyzed. Results The study group before treatment procalcitonin levels were higher than the control group （P〈0.05）; Alter the treatment, the study group of procalcitonin levels were significantly reduced, compared with before treatment had significant difference （P〈0.05）; The study group after the treatment of procalcitonin level and the control group had no significant difference （P〉0.05）. Conclusion Procalcitonin in assessment of neonatal sepsis early diagnosis and treatment and disease the effect of early diagnosis for neonatal sepsis, and take effective measures to improve the prognosis of newborns, worthy of promotion.