卤代喹啉的合成方法研究进展

Research Progress on Synthesis Method of Haloquinolines

卤代喹啉及衍生物具有良好的抗菌、抗肿瘤、抗结核等生物活性,在医药和农药等领域都有广泛的应用。本文综述了卤代喹啉的环合、直接卤代和间接取代等合成方法进展。

Haloquinoline derivatives compounds have good antibacterial, antitumor, anti -tub -erculosis and other biological activity, which were widely used in the field of medicine a - ndpesticides. It was emphasized on the synthetic methods of haloquinoline derivatives, such as cyclization, directive halogenations and halogen substitution.