高铝引起性发育成熟前人和动物的排斥性损害和主动调节保护及自身平衡稳定反应

Exclusionary Damage and Intiative Adjustable Protection and Self-balance Steady Reaction of Human and Animal before Sexual Maturity Caused by High Concentration Aluminium

在铝氟联合中毒的系列研究中 ,发现性发育成熟前头发和血尿高铝的骨软化畸形病人 ,肝、肾铝显著升高的大鼠和鸡的骨铝、脑铝含量在接近或明显甚至显著低于正常对照组时 ,出现了铝骨病和铝危害的其它表现 ;AlCl3 ·6H2 O对童鸡非蓄积危害阈值范围指数 >5 (2 1 40 41 9) ,较低浓度比较高浓度饲铝组病变更为显著 ,铝在一定浓度或剂量范围与反应强度可呈非正相关关系 ;一定浓度以上 ,摄铝与高氟促成铝吸收和蓄积的数倍到 1 0数倍浓度差别的病情差异并不明显。表明人和动物在地壳高铝环境中的长期进化与适应 ,于生长发育旺盛的性成熟前形成并完善了对自然条件下进入内环境高铝的排斥和主动调节保护及自身平衡稳定反应的机制 。

In the studies about fluoride and aluminium symphysic intoxioeation,it found that the osteomalacia patients before sexual maturity whose hair and blood aluminium concentration was high,the rats and cocks whose liver and kidney aluminium inereased but bone and brain aluminium concentration was similar to or less than the normal control group,all have the appearances of the damage of aluminium,such as bone damage.The non accumulation damage threshold index of AlCl 3·6H 2O to young cock is more than 5(2140/419).The damage caused by lower aluminium concentration is more serious than that caused by the higher one.In certain range of dose,aluminium had the negative relationship with the reaction intensity,over certain aluminium concentration,there is no different damage between different intaking and accumulative aluminium caused by high concentration fluoride.It concluded that,just because of the evolution and the adjustment,human and animal get the mechanism of exclusively damage and intiniative adjustable protection and self balance steady reaction,so that they can avoid the damage of aluminium or decrease the intensity of damage.