酒精性肝硬化和病毒性肝硬化病人营养状况调查和分析

Contrast analysis of nutritional status between patients of alcoholic cirrhosis and viral cirrhosis

目的:对比分析酒精性肝硬化和病毒性肝硬化病人的营养状况,为营养支持提供针对性依据。方法:选择酒精性肝硬化病人95例,病毒性肝硬化病人260例,入院后48 h内采用欧洲营养风险筛查2002(NRS2002)和主观整体评估(SGA)法对病人进行评估,记录病人的性别、年龄、肝功能Child-Pugh分级、血清清蛋白(ALB)、前清蛋白(PA)和血红蛋白(Hb)指标,测量病人身高、体重,计算体重指数(BMI)。结果:酒精性肝硬化和病毒性肝硬化病人的NRS 2002营养风险发生率分别为76.80%和65.00%,SGA评估的营养不良发生率分别为67.40%和61.90%。两组病人的性别、Child-Pugh A级、ALB、PA、Hb、NRS 2002筛查等结果差异均有显著性统计学意义。而年龄、Child-Pugh B级、Child-Pugh C级、BMI、SGA评估等结果则无显著性差异。结论:两种类型肝硬化病人普遍存在营养问题,酒精性肝硬化病人的营养风险发生率、贫血程度显著高于病毒性肝硬化病人。

Objective： To compare the nutritional status between alcoholic cirrhosis and viral cir- rhosis, and to provide reference information for the nutritional support strategy. Methods ：95 alcoholic cirrhosis and 260 viral cirrhosis patients were involved in the study. The patients were reviewed with NRS 2002 and SGA within 48 hours after admission. The general information and liver function parameters in- eluding gender, age, BMI, Child-Pugh score, ALB, PA and Hb were recorded. Results ： The NRS 2002 nutritional risk rate of alcoholic cirrhosis and viral cirrhosis patients was 76.80% and 65.00% , respectively. The SGA malnutrition rate of alcoholic cirrhosis and viral cirrhosis patients was 67.40% and 61.90%, respectively. There was statistically significant difference between the two groups in gen- der, Cbild-Pugh A rate, ALB, PA, Hb and NRS 2002, while there was no significant difference in age, Child-Pugh B rate, Child-Pugh C rate, BMI and SGA. Conclusion：Nutritional dysfunction exists in both of the two types of liver cirrhosis. The nutritional risk rate and the anemia rate in alcoholic cirrhosis patients are significantly worse than those in viral cirrhosis patients.