脱落细胞学在慢性口腔溃疡中的诊断价值

Diagnostic value of exfoliative cytology for chronic oral ulcers

目的探讨脱落细胞学检查在各种慢性口腔溃疡中的诊断价值。方法选取107例临床难以确定其溃疡性质的慢性口腔溃疡行脱落细胞学检查。术后病理或临床治疗效果验证作为最终诊断,最终诊断与细胞学检查结果进行对比分析。结果脱落细胞学检查定性诊断的准确率为95.3%,良恶性病变的敏感性为94.6%,特异性为100%,假阳性率为0,假阴性率为5.4%,细胞学检查与最终病理诊断结果完全一致的符合率为67.0%。结论脱落细胞学检查对于慢性口腔溃疡诊断具有重要的参考价值,其具有简单易行、快速、创伤小等特点,医师可根据细胞学检查结果制定下一步诊疗计划。

Purpose To evaluate the effectiveness of exfoliative cytology in chronic oral ulcers diagnosis. Methods To examined 107 cases of chronic oral ulcers which were difficult to determine the nature of the ulcer in exfoliaticve cytology, and compared postoperative histopathological results or clinical results, and made the final diagnosis with cytology. Results The qualitative diagnostic accuracy of cytology was 95.3%. The sensitivity and specificity for benign and malignant lesions was 94. 6% and 100% , respectively. False positive rate was 0, and false negative rate was 5.4%, and the coincidence rate of cyto- logical examination with the final pathology was 67.0%. Conclusion Exfoliative cytology has important reference value in chronic oral ulcer diagnosis. It is characterized by simple, rapid procedure and less trauma. Doctors can develop next treatment plan based on the results of exfoliative cytology.