贵州产赤胫散药材的质量分析

A Quality Analysis on Polygonum runcinatum from Guizhou Province

目的:对贵州赤胫散的水分、杂质、灰分和酸不溶性灰分、农药残留量、干燥失重、炽灼残渣及浸出物进行测定,为控制赤胫散药材的质量提供实验依据。方法:按照《中国药典》中水分(烘干法)、杂质、灰分、农药残留量、干燥失重、炽灼残渣、浸出物的测定方法对贵州赤胫散进行测定。结果:贵州产的15批赤胫散药材杂质含量为0.05%~0.84%,水分含量为12.72%~13.40%,干燥失重结果为12.44%~13.94%,总灰分含量为2.04%~3.40%,酸不溶性灰分含量为0.33%~1.47%,炽灼残渣结果为2.52%~3.70%,水溶性浸出物含量为34.31%~38.45%,15批赤胫散药材均未检出8种有机氯残留农药。结论:实验结果为提升赤胫散药材的质量标准提供了科学依据。

Objective： To determine the contents of moisture, impurity, ash, acid insoluble ash, pesticide residue, dry weight loss, residue, and extract from Polygonum runcinatum of Guizhou, and to provide experimental basis for medicinal material quality control. Methods：The methods recorded in the Chinese Pharmacopoeia were adopted in the determination of moisture, impurity, ash, acid insoluble ash, pesticide residue, dry weight loss, residue, and extract. Totally, 15 batches of Polygonum runcinatum were checked. Results：In the 15 batches of Polygonum runcinatum, moisture content range was 12.72% - 13.40% ; impurity content 0.05% - 0.84% ; total ash content 2.25% - 3. 40% ; acid insoluble ash content 0.33% - 1.47% ; ignition residue 2.54% -3.70% ; dry weight loss 12.44% - 13.94% ; water extract 34.31% - 38.45%. Residue of 8 pesticides did not detected. Conclusion：This study provides scientific basis for promoting quality standard of Polygonum runcinaturn.