反复呼吸道感染患儿血清维生素A、D、E水平与骨密度的关系

Relationship of Serum Vitamin A,D and E Levels with Bone Mineral Density in Children with Recurrent Respiratory Tract Infection

目的:观察反复呼吸道感染(RTIs)患儿血清维生素A、D、E水平及其与骨密度的关系。方法:选取RTIs复感儿52例作为患儿组,正常体检儿童52例作为对照组,检测血清维生素A、D、E水平,同时检测血清钙及血清骨钙素水平,X线检查股骨粗隆处骨密度,并对RTIs患儿血清维生素A、D、E水平与骨密度进行相关性分析。结果:患儿组维生素A、D、E,血清钙及骨钙素较对照组低,两组比较差异有统计学意义(P<0.05);X线检查结果显示,患儿组骨密度较对照组低,两组比较差异有统计学意义(P<0.05);RTIs患儿维生素A、D、E中单一维生素缺乏或两种及两种以上维生素缺乏与骨密度水平呈正相关关系。结论:RTIs患儿血清维生素A、D、E缺乏与骨密度低呈正相关关系,血清维生素A、D、E降低可能是引起骨密度下降的原因。

Objective： To explore the relationship between serum vitamin levels and bone mineral density （BMD） in children with recurrent respiratory tract infection （RTIs）. Methods： 52 cases of children with RTIs served as patient group, 52 cases of normal children served as control group. Serum vitamin A, D, E levels, serum calcium, serum osteocalcin, bone metabolism and femoral trochanter BMD were examined, and the correlation between serum vitamin levels and BMD was anlayzed. Resuits： The vitamin A, D, E contents, serum calcium and osteocalcin levels of patient group were lower than the control group （P 〈 0.05 ） ; the BMD of patient group children were lower than the control group （P 〈 0.05） ; vitamin levels of children with vitamin A, D, E deficiency were positively correlated with BMD. Conclusion： RTIs can reduce the serum level of vitamin in children, and the decrease of vitamin levels can cause the decrease of BMD.