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健康儿童接种7价肺炎链球菌结合疫苗可减少该菌所致的疾病 被引量:1

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摘要 健康儿童鼻咽部肺炎球菌的无症状携带很常见,一种包含常见致病菌血清型的7价肺炎链球菌结合疫苗能有效避免鼻咽部携带肺炎链球菌。作者评价了健康儿童鼻咽部肺炎链球菌的流行率,测定了其对多种抗生素的耐药性,找出了引起携带的危险因素,并阐明了1岁以内儿童接种该疫苗的意义。 方法:2000年4月15日~6月15日。
作者 张世勇
出处 《国外医学(流行病学.传染病学分册)》 2002年第4期253-254,共2页 Epidemiology Lemology Foreign Medical Sciences
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  • 1江山,杨耀.肺炎球菌疫苗的发展和现状[J].上海预防医学,2006,18(12):640-642. 被引量:6
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  • 7林子琳.肺炎球菌表面蛋白A(PspA)的克隆表达及交叉免疫学特性研究.福州大学硕士毕业论文,2008.
  • 8Miyaji EN, Ferreira DM, Lopes APY, et al. Analysis of serum cross-reactivity and cross-protection elicited byimmunization with DNA vaccines against Streptococcus pneumoniae expressing PspA fragments from different clades. Infect lmmun, 2002, 70(9): 5086-90.
  • 9黄金钟,林海英,蔡倩影,郭养浩,孟春.肺炎球菌表面蛋白A(PspA)及其荚膜多糖交联物的免疫原性和交叉保护作用[J].生物化学与生物物理进展,2008,35(5):536-539. 被引量:3

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