昆明地区0～12岁儿童血浆25-(OH)D水平

Levels of 25-(OH)D in 0～12 years Old Children in Kunming

目的了解昆明地区0～12岁儿童血浆25-（OH）D的水平和现状．方法应用罗氏公司Rochecobas8000／E602全自动电化学发光免疫分析系统对昆明地区4区8县0-12岁4489例儿童进行血浆25-（OH）D水平的检测，应用SPSS统计软件进行统计分析．结果随着年龄的增大，血浆25-（OH）D浓度逐渐降低，各年龄组血浆浓度比较差异有统计学意义（P〈0．05）；男女2组血浆25-（0H）D浓度比较，结果差异无统计学意义（P〉0．05）；昆明地区儿童维生素D平均水平是83．48nm01]L，0-l岁组儿童血浆25-（OH）D浓度呈分散性分布，6-9岁组血浓度分布最集中．结论昆明地区0-12岁儿童维生素D水平总的处于一个良好的营养状况，但随着年龄的增长，维生素D营养水平逐渐降低，尤其3岁以后降低明显，均处于不足或缺乏状态，应引起大家的重视．

Objective To learn the levels of serum 25- （OH）D in 0-12 years old chindren in Kunming. Methods Serum 25- （OH）D levels of children （4 498） were measured by using Roche cobas 8 000 / E602 automatic electrochemical luminescence immunoassay. Results As the increase of age, the levels of serum 25- （OH）D were gradually decreased, different age groups had significant difference （P〈0.05）. The levels of 25- （OH）D between boys and girls had no significant difference （P〉O.05） ; The average level of sernm 25- （OH）D was 83.48 nmol/L, the level of serum 25-（OH）D was distributed in 0 - 1 years old group, and most concentrated in the 6 - 9 years old group. Conclusion The levels of 25-（OH）D in 0-12 years old chindren are in a good status, but with the increase of age, the level of 25- （OH）D is decreasing gradually, especially the levels of 25- （OH）D decreased significantly after the age of three, in shortage or lack of status, this should cause everybody＇s attention.