贵州疾病监测县1～29岁乙肝血清标志物五项全阴人群动态分析

Analysis of the negative proportion of the five-index of HBVM among population aged 1～29 years in monitoring countiesin Guizhou

目的研究贵州省疾病监测县1~29岁人群中乙肝血清标志物五项全阴者的分布特征及动态变化,为我省进一步加强乙肝防控提供依据。方法根据我省5个疾病监测县2006年和2014年两次血清流行病学调查的数据资料,对1~29岁乙肝血清标志物五项全阴的人群进行描述性流行病学分析。结果 2014年监测县1~29岁人群中乙肝五项全阴占比为41.33%,较2006年减少7.85%,降幅为15.97%,差异有统计学意义(P﹤0.05)。不同特征人群存在差异,5~14岁儿童降幅12.17%,汉族降幅24.42%,两次调查差异有统计学意义(P﹤0.05);少数民族升幅11.48%,农民升幅21.04%,两次调查差异无统计学意义(P﹥0.05)。1~29岁人群HBs Ab阳性率2014年较2006年增长19.51%,HBs Ag阳性率下降36.68%。结论贵州疾病监测县乙肝五项全阴人群总体呈下降趋势,易感人群减少;不同特征人群变化存在差异,1~14岁儿童、汉族降幅明显,提示该部分人群乙肝防控成效显著;应加强对大年龄人群、少数民族和农民人群的免疫接种和乙肝防治健康教育。

Objective To study the status of the negative population of five-index of HBVM aged 1-29 years in monitoring counties in Guizhou, find the distrbution characterstics and the variation trend so as to provide evidence for the strategies on hepatitis B prevention and control. Methods Analyzed the seroepidemiological survey data in china in 2006 and 2014,by descriptive epidemiological method.The target population are the 1-29 years old in Guizhou. Results Among the !~29 years-old population,the proportion of the negative population of five-index of HBVM is 41.33%,fell by 15.97%, the difference have statistical significance. The reduced and decreased amplitude are different in different characteristic populations. The 5-14 years-old population fell by12.17%, Hart nation fell by24.42%, the differences have statistical significance in the two investigations.Among the 1-29 years-old population,the positive rate of HBsAb grew by 19.51%. the positive rate of HBsAg fell by 36.368%. Conclusion The proportion is reduced in the general population in Guizhou, the susceptible population is reduced; The variation trends are different in different characteristic populations; The reduced amplitudes are obvious in the 1-14 years-old population and Han nation.lt indicate that the achievement of the Prevention and Control of HBV is outsanding in these populations. We should further strengthen the vaccination of HepB and health education for the negative population of five-index of HBVM, especially for the older than 15 years minority and peasant.