左房内径、血清尿酸水平与老年心房颤动的相关性分析

A Study on the Correlation of Left Atrial Diameter and Serum Uric Acid Level with the Atrial Fibrillation in Elderly Patients

目的:探讨左房内径(LAD)、血清尿酸(UA)水平与老年心房颤动的相关性。方法:选择2013年1月至2016年7月在我院住院的60岁以上的非瓣膜性房颤患者,共166例,其中持续性房颤组85例,阵发性房颤组81例,选择同期无房颤的高血压、冠心病老年患者83例作对照组。通过心脏彩超检查检测LAD、左心室舒张末期内径(LVDD)、左心室收缩末期内径(LVDS)、左心室射血分数(LVEF),以≥40 mm为左房内径增大。并采用生化分析检测患者血清UA水平。结果:(1)持续性房颤组LAD、LVEF、左心房增大发生率均显著高于阵发性房颤组和对照组,而阵发性房颤组以上指标均明显高于对照组,差异具有统计学意义(P<0.05)。(2)持续性房颤组和阵发性房颤组患者血清UA水平均显著高于对照组,但持续性房颤组和阵发性房颤组之间血清UA水平比较差异无统计学意义(P>0.05)。结论:左心房内径大小、血尿酸水平与老年患者心房颤动的发生密切相关。

Objective： To explore the correlation of Left atrial diameter （LAD） and serum level of uric acid （UA） with atrial fibril- lation in elderly patients. Methods： A total of 166 patients with non-valvular atrial fibrillation （AF） who were hospitalized in our hospital from January 2013 to July 2016 were enrolled, including 85 patients with persistent AF and 81 patients with paroxysmal AF. High blood pressure of atrial fibrillation, coronary heart disease in 83 elderly patients as the control group. Patients were given color Doppler ultra- sound examination, measured LAD and LVEF, the diameter of left atria ~ 40 mm as left atria increased. And test the serum UA level of patients by using biochemical analysis testing. Results： 1. The incidence of LAD, LVEF and left atrial enlargement in persistent atrial fib- rillation group was higher than that in paroxysmal atrial fibrillation group and paroxysmal atrial fibrillation group, and the difference was statistically significant （P〈0.05）. 2. Persistent AF group and the patients with paroxysmal atrial fibrillation group were significantly higher than that of control group, serum levels of UA but persistent of group and paroxysmal atrial fibrillation group comparison between serum UA level difference has no statistical significance （P〉0.05）. Conclusions： The size of left atrium and the level of serum uric acid are closely related to the occurrence of atrial fibrillation in elderly patients.