克霉唑阴道片治疗复发性假丝酵母菌性阴道炎的临床效果研究

Clinical effect of clotrimazole vaginal tablets in the treatment of recurrent candida vaginitis

目的:分析并探讨克霉唑阴道片治疗复发性假丝酵母菌性阴道炎的临床效果,从而为临床治疗方案选择提供依据。方法:选取2012年1月至2015年1月期间在我院接受治疗的复发性假丝酵母菌性阴道炎患者160例,随机分为观察组与对照组。观察组采用克霉唑阴道片治疗,对照组采用达克宁治疗。结果:两组患者治疗后临床症状均明显改善,观察组改善更加明显(P<0.05)。观察组有效率为86.3%,对照组有效率为71.3%,观察组有效率明显高于对照组(P<0.05)。观察组不良反应发生率为7.5%,对照组为13.8%,两组不良反应发生率无显著差异(P>0.05)。观察组随访复发率为10.0%,对照组为22.5%,观察组复发率明显低于对照组(P<0.05)。结论:克霉唑阴道片治疗复发性假丝酵母菌性阴道炎的临床效果显著,不良反应少,复发率低,临床上值得推广。

Objectives： To analyze and discuss the clinical effect of clotrimazole vaginal tablets in the treat- ment of recurrent Candida vaginitis, thus providing basis for the clinical treatment options. Methods： 160 patients in our hospital for treatment of recurrent Candida vaginitis from January 2012 to January 2015 were selected and ran- domly divided into observation group and control group. Observation group received clotrimazole vaginal tablets for treatment and the control group received Miconazole for treatment. Results： The clinical symptoms were significantly improved in both groups, more significant in the observation group （ P 〈 0. 05 ）. The effective rate of observation group and control group was 86. 3% and 71.3% respectively, with significant difference （P 〈 0. 05 ）. The inci- dence of adverse reactions in the observation group and control group was 7.5% and 13.8% respectively, without significant difference （ P 〉 0. 05 ）. In the follow - up, the recurrence rate of observation group and control group was 10. 0% and 22.5% respectively, with significant difference （P 〈 0. 05 ）. Conclusion： Clotrimazole vaginal tablets are of significant clinical effect in the treatment of recurrent Candida vaginitis, with few adverse reactions and low recurrence rate, thusly worthy of clinical application.