糖调节受损患者合并代谢综合征与发生心脑血管疾病的相关性分析

Correlation between metabolic syndrome and cardiovascular disease in patients with impaired glucose regulation

目的探讨代谢综合征对糖调节受损人群发生心脑血管疾病的影响。方法将2010年1月至2012年12月收治的糖调节受损患者作为研究对象,根据患者是否合并代谢综合征(MS)分成MS组和非MS组,随访至2015年12月,记录患者是否发生心脑血管疾病,比较两组患者心脑血管疾病事件的发生率。结果共有38例患者发生心脑血管疾病,发生率为11.0%。MS组23例(19.0%),非MS组15例(6.7%),组间比较差异有统计学意义(χ~2=12.041,P<0.05)。结论糖调节受损合并代谢综合征的患者相较于单独糖调节受损患者更易发生心脑血管疾病,糖调节受损合并代谢综合征的患者不仅要控制血糖,还要对MS的每一种组分进行针对性的综合干预。

Objective To investigate the effect of metabolic syndrome on cardiovascular and cerebrovascular diseases in patients with impaired glucose regulation.Methods According to the standard,the impaired glucose regulation patients who saw a doctor in the department of endocrinology of our hospital from January 2010 to December 2012,were drown into the study.They were divided into metabolic syndrome group and non metabolic syndrome group,based on whether with metabolic syndrome.And they were followed-up visit up to December 2015,in order to record whether be attacked by cardiovascular and cerebrovascular diseases.Then the incidence of two groups cardiovascular and cerebrovascular diseases were compared.Results There were 38 cases of patients with cardiovascular and cerebrovascular diseases,the incidence was 11.0%,with metabolic syndrome group of 23 cases（ 19.0%）,non metabolic syndrome patients group of15 cases（ 6.7%）,the difference was statistically significant（ χ^2= 12.041,P〈0.05）.Conclusions Compared with non metabolic syndrome patients,it is more susceptible to be attacked by cardiovascular and cerebrovascular diseases.It is necessary to control blood glucose,and give comprehensive intervention of each component of metabolic syndrome,in the clinical treatment or to prevent cardiovascular disease for impaired glucose regulation patients with metabolic syndrome.