辨证分型治疗眩晕随机平行对照研究

Random Parallel Control Study on Traditional Chinese Medicine Dialectical Treatment of Vertigo

[目的]观察辨证分型治疗眩晕疗效。[方法]使用随机平行对照方法,将84例门诊患者按病志号抽签方法简单随机分为两组,治疗组按证型纳入痰浊上蒙、脾虚肝旺、肝肾阴虚三个亚组。对照组43例尼莫地平胶囊,30~120mg/次,3次/d,口服。治疗组41例,中药汤剂口服,1剂/d,早晚分服;痰浊上蒙-化痰息风(半夏、陈皮各10g,茯苓15g,石菖蒲10g,白术20g,天麻、竹茹各10g);脾虚肝旺-健脾疏肝(党参、山药、白术、茯苓、生薏米各20g,枸杞、香附、柴胡、合欢皮各15g);肝肾阴虚-补益肝肾(山萸肉、枸杞果、熟地、龟板、龙骨、牡蛎各15g,地骨皮、丹皮各10g,麦冬、酸枣仁、钩藤、天麻、杜仲、桑寄生各15g,香附20g),连续治疗30d为1疗程。观测临床症状、血压、血脂、心电图及其不良反应。治疗1疗程(30d),判定疗效。[结果]治疗组痊愈11例,显效17例,有效8例,无效5例,总有效率87.80%;对照组痊愈9例,显效15例,有效10例,无效9例,总有效率79.07%;治疗组疗效优于对照组(P<0.05)。[结论]辨证分型治疗眩晕,疗效满意,无严重不良反应。

[Objective] To observe the curative effect of traditional Chinese medicine dialectical treatment of vertigo. [Methods] Using random parallel control method, 84 cases of outpatients were randomly divided into two groups. The treatment group was divided into three subgroups： 43 cases of the control group had nim horizon capsule, 30-120mg/time, 3 times/d, oral. The treatment group was including 41 cases, and had medicinal broth of oral Chinese medicine in the morning and evening, daily agent; Phlegm turbidity in Mongolia-phlegm XiFeng （pinellia 10g, orange peel lOg, poria cocos 15g, stone calamus 10g, atractylodes 20g, gastrodia clara log, bamboo shavings 10g）; Spleen deficient to liver strong-invigoring spleen and smoothing liver （dangshen, yam, each 20g atractylodes, poria cocos, coix seed, Chinese wolfberry, incense, radix bupleuri, cortex albiziae each 15g）; Liver and kidney Yin deficiency-tonic liver and kidney （comus, wolfberry fruit, prepared rhizome of rehmannia, tortoise plastron, keel, oysters, each 15g, Dan skin to skin and bones, lOg each, dwarf lilyturf, zizyphus jujube kernel, uncaria, gastrodia elata, eucommia bark, mulberry parasitism each 15g, spiced with 20g）. It was 1 course to have been treated for 30d. Observing clinical symptoms, blood pressure, blood lipid, electrocardiogram （ecg） and its adverse reactions, then judging curativeeffect after treated 1 course （30d）. [Results] in treatment group, 11 cases were recovered, 17 cases had marked effect, 8 cases had effective, 5 cases were invalid, and the total effective rate was 87.80%; in control group, 9 cases were recovered, 15 cases were markedly effective, 10 cases had effective, 9 cases were invalid, the total effective rate was 79.07%; The treatment group curative effect is better than that of control group （P〈0.05）. [Conclusion] Traditional Chinese medicine dialectical treatment of vertigo is satisfied and have no serious adverse reactions.