棒状光源盐酸5-氨基酮戊酸光动力治疗肛管内尖锐湿疣

Topical 5-aminolevulinic acid photodynamic therapy with stick light source in the treatment of intra anal-rectal warts

目的:评价棒状光源盐酸5-氨基酮戊酸光动力疗法治疗肛管内尖锐湿疣的临床疗效。方法:棒状光源盐酸5-氨基酮戊酸治疗肛管内尖锐湿疣男性患者46例,每周1次,共4次。结果:35例(76.1%)患者疣体完全清除,无感染、溃疡、瘢痕、痔疮病例。随访12周复发5例,复发率为14.3%。疼痛程度可视模拟评分(VAS)为(6.96±1.41)分。结论:棒状光源盐酸5-氨基酮戊酸治疗肛管内尖锐湿疣疗效好,中度疼痛,复发率低,不良反应少。

Objective：To assess the efficacy of hydrochloric 5-aminolevulinic acid photodynamic therapy （ALA-PDT） with stick light source in the treatment of intra anal-rectal warts.Methods：Forty-six male patients with intra anal-rectal warts were treated with ALA-PDT （stick light source）, once a week for 4 weeks.Results：The warts body was completely removed in 35 cases （76.1%）.There was no infection, ulcer, scar and hemorrhoids.Five patients recurred after 12 weeks of follow-up with a recurrence rate of 14.3%.The score of pain visual analogue scale （VAS） was 6.96±1.41 points.Conclusion：ALA-PDT with stick light source in the treatment of intra anal-rectal warts had good effect, moderate pain low recurrence rate and less adverse reactions.