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艾塞那肽致体温降低一例

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摘要 胰高血糖素样肽1（GLP-1）能通过促进胰岛β细胞的增殖，增加β细胞分泌胰岛素、减少α细胞分泌胰高血糖素，显著降低2型糖尿病（T2DM）患者糖化血红蛋白（HbA1c）水平。艾塞那肽作为首个获准上市的GLP-1受体激动剂（GLP-1RA），还可抑制食欲，延缓胃排空，从而进一步减轻体重。T2DM患者长期接受艾塞那肽治疗获益颇多，
作者 朱红艳 朱宁 沈云峰
机构地区 南昌大学第二附属医院内分泌代谢科
出处 《中华糖尿病杂志》 CAS CSCD 2017年第4期254-255,共2页 CHINESE JOURNAL OF DIABETES MELLITUS
关键词 胰高血糖素样肽 体温降低 胰岛Β细胞 糖化血红蛋白 分泌胰岛素 2型糖尿病 受体激动剂 GLP-1
分类号 R587.1 [医药卫生—内分泌]
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二级参考文献30

  • 1Holman RR,Paul SK,Bethel MA. 10-year follow-up of intensive glucose control in type 2 diabetes[J].New England Journal of Medicine,2008.1577-1589.
  • 2Drucker D J,Nauck MA. The incretin system:glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes[J].The Lancet,2006.1696-1705.
  • 3Drucker DJ. Glucagon-like peptides:regulators of cell proliferation,differentiation,and apoptosis[J].Molecular Endocrinology,2003.161-171.
  • 4Drucker DJ. Develpoment of glucagon-like peptide-1-based pharmaceuticals as therapeutic agents for the treatment of diabetes[J].Current Pharmaceutical Design,2001.1399-1412.
  • 5Garg SK. The role of basal insulin and glucagon-like peptide-1 agonists in the therapeutic management of type 2 diabetes-a comprehensive review[J].Diabetes Technology and Therapeutics,2010.11-24.
  • 6Russell-Jones D,Vaag A,Schmitz O. Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met +SU):a randomised controlled trial[J].Diabetologia,2009.2046-2055.
  • 7Bunck MC,Diamant M,Cornér A. One-year treatment with exenatide improves beta-cell function,compared with insulin glargine,in metformin-treated type 2 diabetic patients:a randomized,controlled trial[J].Diabetes Care,2009.762-768.
  • 8Barnett AH,Burger J,Johns D. Tolerability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2diabetes previously uncontrolled with metformin or a sulfonylurea:a multinational,randomized,open-label,two-period,crossover noninferiority trial[J].Clinical Therapeutics,2007.2333-2348.
  • 9Heine RJ,Van Gaal LF,Johns D. Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes:a randomized trial[J].Annals of Internal Medicine,2005.559-569.
  • 10Sheffield CA,Kane MP,Busch RS. Safety and efficacy of exenatide in combination with insulin in patients with type 2diabetes mellitus[J].Endocrine Practice,2008.285-292.

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中华糖尿病杂志
2017年 第4期

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