猪苓汤联合呋喃妥因治疗复发性尿路感染48例

Zhuling Decoction Combined with Furadantin in the Treatment of Recurrent Urinary Tract Infection for 48 Cases

目的探讨猪苓汤联合呋喃妥因治疗复发性尿路感染的疗效及安全性。方法选择2013年11月—2015年11月在辽阳市中医院就诊的96例复发性尿路感染患者为研究对象,随机分成观察组(猪苓汤联合呋喃妥因治疗)48例和对照组(呋喃妥因治疗)48例,比较2组临床疗效和用药安全性。结果观察组总有效率(95.83%)显著高于对照组(79.17%),差异有统计学意义(P<0.05);观察组主要症状消失时间(5.54±1.86)天显著低于对照组(8.34±2.92)天,差异有统计学意义(P<0.01);观察组复发率(54.17%)显著低于对照组(75%),差异有统计学意义(P<0.05);观察组药物不良反应发生率(18.75%)与对照组(16.67%)比较,差异无统计学意义(P>0.05)。结论猪苓汤可以有效提高复发性尿路感染疗效,降低复发率,且用药安全性好。

Objective To explore the therapeutiv effect and safety of Zhuling decoction combine with Furadantin in the treatment of recurrent urinary tract infection（RURI）.Methods A total of 96 cases of patients with RURI in Liaoyang Hospital of Traditional Chinese Medicine from November 2013 to November 2015 were randomly divided into the observation group of 48 cases was treated with Zhuling decoction combine with Furadantin and control group of 48 cases was treated with Furadantin.The difference of clinical curative effect and medication safety were compared between the two groups.Results The total effective rate in the observation group（95.83%） was significantly higher than that in the control group（79.17%）（P0.05）.The disappearance time of main symptoms in the observation group（5.54±1.86） days was significantly lower than that in the control group（8.34±2.92） days（P0.05）.The recurrence rate in the observation group（54.17%） was significantly higher than that in the control group（75%）（P 0.05）.There was no significant difference on adverse reactions between the observation group（18.75%） and the control group（16.67%）（P 0.05）.Conclusion Zhuling decoction could effectively improve the curative effect,and reduce the recurrence rate of RURI.There have no obvious adverse reactions.