美洲大蠊抗肿瘤作用研究进展

Research Progress on the Anti-tumor Effect of Periplaneta Americana

近些年来人们对美洲大蠊药理作用研究越来越多,美洲大蠊具有资源丰富、临床应用广泛等特点。美洲大蠊具有抗肿瘤、抗炎、抗病毒、组织修复、镇痛、保肝、抗氧化及增强免疫作用。美洲大蠊对多种肿瘤细胞均有抑制生长及增殖,如肝癌、肺癌、胃癌、结肠癌、食管癌、前列腺癌、宫颈癌、卵巢癌、白血病及小鼠转移细胞瘤,并能诱导肿瘤细胞凋亡。该文对美洲大蠊抗肿瘤作用进行深入综述,为深入研究和临床应用提供依据。

In recent years, the pharmacological action research of periplaneta americana is more and more. Periplaneta americana has the characteristics of rich resources and wide clinical application. Periplaneta americana has immune antitumor effect, anti-inflamma- tory, antiviral, tissue repair, analgesic, antioxidant and hepatoproteetive, enhancing immunity function. Periplaneta americana can in- hibit the growth and proliferation of various tumor cells, such as liver cancer, lung cancer, gastric cancer, colon cancer, esophageal cancer, prostate cancer, cervical cancer, ovarian cancer, leukemia and metastasis of mouse tumor cells, and an induce apoptosis of tu- mor cells. The effect of periplaneta americana on the anti-tumor was reviewed in this paper, in order to provide the basis for further research and clinical application.