声速匹配技术定量诊断非酒精性单纯性脂肪肝

Quantitative diagnosis of nonalcoholic simple fatty liver by sound speed correction

目的探讨声速匹配(SSC)技术定量诊断非酒精性单纯性脂肪肝的价值。方法选择26例非酒精性单纯性脂肪肝患者为脂肪肝组,37例健康体检者为对照组,应用声速匹配测量受检者肝脏右叶s5~s8段及肝脏中心区域的区域声速指数、区域声速值以及肝脏右叶斜径。结果脂肪肝组患者肝脏右后叶各段声速值显著高于对照组,差异有统计学意义(P均<0.05),两组患者右前叶各段及肝脏中心区域的声速值差异无统计学意义(P均>0.05)。脂肪肝组患者区域声速指数与肝脏右叶斜径呈正相关(r=0.42,P=0.032),回归方程为y=0.84x-103.1。结论声速匹配技术对定量诊断非酒精性单纯性脂肪肝有一定价值,值得进一步深入研究。

Objective To evaluate the value of sound speed correction （SSC） in the quantitative diagnosis of nonalcoholic simple fatty liver （NAFL）. Methods Total of 26 patients with NAFL were selected as NAFL group and 37 healthy controls were selected as control group. SSC, the zone speed index （ZSI）, zone sound speed （ZSS） of hepatic segments s5-s8 and hepatic central area were measured. At the same time,the inclined diameter of the right hepatic lobe and the portal vein＇s diameter were measured. Results The ZSS of hepatic segments s6-s7 in NAFL group were higher than those of control group, the differences were statistically significant （P 〈 0.05）. However, the ZSS of hepatic segments s5 and s8 had no statistical differences between two groups （P 〉 0.05）. In NAFL group, ZSI and inclined diameter of the right hepatic lobe was positively correlated （r = 0.42,P = 0.032）, and the regression equation is y = 0.84x -103.1.Conclusions SSC has certain value in quantitative diagnosis of NAFL, and it is worthy of further research for accurate classification of the degree of NAFL.