慢性阻塞性肺疾病临床问卷对稳定期慢性阻塞性肺疾病生活质量的评价

Investigation of COPD Clinical Questionnaire for Evaluating Quality of Life of Patients with Chronic Obstructive Pulmonary Disease in Stable Period

目的探讨慢性阻塞性肺疾病(COPD)临床问卷(CCQ)对稳定期COPD患者生活质量的评价作用。方法选择2014年12月—2015年12月收治的105例稳定期COPD患者,均接受肺功能、圣乔治呼吸问卷(SGRQ)、COPD评估测试(CAT)、英国医学研究委员会调查问卷(MMRC)与CCQ调查,分析不同评价指标间的相关性。结果SGRQ问卷完成时间、协助比例均长于或高于CAT、MMRC、CCQ问卷,不同GOLD分级SGRQ、CAT、MMRC、CCQ、用力肺活量(FVC)、第1秒用力呼气未容积(FEV1)、FEV1/FVC比较差异有统计学意义(P<0.05)。SGRQ、CAT、MMRC、CCQ问卷评分间呈正相关,且各问卷与肺功能指标呈负相关(P<0.05);CAT、MMRC对高风险患者评估结果一致,而对低风险和患者评估结果差异显著,CCQ、CAT对低风险和高风险患者评估结果均一致(P<0.001,P<0.05)。结论SGRQ、CAT、MMRC、CCQ问卷均与COPD肺功能相关,可作为生活质量评价重要方法,但SGRQ比较复杂,需协助完成,耗时较长;CCQ或CAT评分对COPD患者症状评估效果更好。

Objective To evaluate effect of chronic obstructive pulmonary disease （COPD） clinical questionnaire （CCQ） in evaluating the quality of life of patients with COPD in stable period. Methods A total of 105 patients COPD in stable period admitted during December 2014 and December 2015 received survey of pulmonary function, St. George Respiratory Questionnaire （SGRQ）, COPD Assessment Test （CAT）, test to assess the British Medical Research Council （MMRC） questionnaire and COPD CCQ. The relationship between different evaluation indexes was analyzed. Results Values of completion time and assistance ratio by SGRQ were significantly higher than those by CAT, MMRC and CCQ. There were significant differences in forced vital capacity （FVC）, forced expiratory volume in one second （FEV1） and FEV1/FVC among SGRQ, CAT, MMRC and CCQ in different GOLD grades （P 〈0. 05）. SGRQ, CAT, MMRC and CCQ scores were positively correlated （P 〈 0.05 ）, and every questionnaire score was negatively correlated with its lung function indexes （P 〈 0.05）. CAT and MMRC were consistent in evaluation of high-risk patients, while there was significant difference in evaluation of low-risk patients （P 〈 0. 001, P 〈0. 05 ）. CCQ and CAT were consistent in evaluation of low-risk and high-risk patients （P 〈 0. 001 ）. Conclusion SGRQ, CAT, MMRC and CCQ are correlated with pulmonary function in patients with COPD, and therefore it can be used as important methods to evaluate quality of life of the patients. SGRQ is more complex, and it needs assist to complete the evaluation with time-consuming. CCQ or CAT score is better in evaluation of the symptoms of patients with COPD.