大隐静脉顺行序贯式吻合技术在冠状动脉旁路移植术中的应用

Antegrade sequential anastomosis of great saphenous veins in off-pump coronary artery bypass grafting

目的总结冠状动脉粥样硬化性心脏病患者在非体外循环下应用大隐静脉顺行序贯式吻合技术行冠状动脉旁路移植术的治疗效果。方法 2013年1月至2015年6月,连续116例冠状动脉粥样硬化性心脏病患者在我院非体外循环下行顺行序贯式冠状动脉旁路移植术,其中男63例,女53例,平均年龄42~80(64.26±9.67)岁。采用左乳内动脉搭桥左前降支,其余各支靶血管以大隐静脉行顺行序贯式搭桥,首先吻合大隐静脉与升主动脉近端,再顺行序贯吻合对角支、回旋支、钝缘支、左室后支、后降支。结果全组患者无死亡,无围术期心肌梗死。桥血管吻合数目共436个,平均(3.75±0.53)个/例。术后低心排血量综合征3例,经给予血管活性药物联合应用主动脉内球囊反搏(IABP)治疗后痊愈。迟发性心脏压塞1例,急性肾功能衰竭1例,均治愈,患者心绞痛症状均消失,活动量明显增加而无明显不适。结论冠状动脉粥样硬化性心脏病在非体外循环下采用顺行序贯式吻合技术行冠状动脉旁路移植术,可减少主动脉吻合口,节约桥血管长度,缩短手术时间,并可最快恢复心脏供血,是一种安全、有效的冠状动脉手术技术。

Objective To summarize the treatment outcomes of antegrade sequential anastomosis of great saphenous veins in off-pump coronary artery bypass grafting for coronary atherosclerotic heart disease. Methods A total of 116 patients with coronary atherosclerotic heart diseases underwent off-pump coronary artery bypass grafting from January 2013 to June 2015 in our hospital. There were 63 males and 53 females with a mean age of 42–80 （64.26±9.67） years. Left internal mammary artery was anastomosed to left anterior descending artery. The rest of the target vessels received antegrade sequential anastomosis of great saphenous veins with the order of proximal ascending aorta, diagonal branch, circumflex branch, obtuse marginal branch, left ventricular branch and posterior descending artery. Results All patients were performed off-pump coronary artery bypass grafting successfully without death or perioperative myocardial infarction. A total of 436 grafts were adopted with 3.75±0.53 in each patient. Three patients suffered low cardiac output syndrome, and were cured after administration of vasoactive drugs combined with the intra-aortic balloon pump. One patient suffered tardive pericardial tamponade and one acute renal failure, who were cured with disappearance of angina symptoms and increase of activities without discomfort. Conclusion Antegrade sequential anastomosis, as a safe and effective method, can reduce aortic stoma, save the length of grafts, shorten operative time and quickly restorate blood supply of myocardium in off-pump coronary artery bypass grafting.