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异体CIK联合化疗治疗晚期恶性肿瘤的疗效分析

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摘要 为了分析比较异体CIK细胞联合化疗治疗晚期恶性实体肿瘤与单纯化疗治疗晚期恶性实体肿瘤的临床疗效。回顾性观察分析了2013年11月至2015年11月同期在武汉紫荆医院住院的42例晚期恶性实体肿瘤患者,按治疗方式不同分成治疗组和对照组。治疗组21例,给予异体血CIK培养后进行细胞输注治疗,至少使用2周期,期间给予化疗治疗;对照组21例,给予单纯化疗治疗。3月后判断临床疗效。结果表明:治疗组疾病控制率是80.95%,对照组疾病控制率率61.90%,治疗组有效率52.38%,对照组有效率28.57%,2组比较p﹤0.05两组患者临床疗效差异有显著意义;治疗组KPS评分较对照组明显改善,骨髓抑制的情况联合治疗明显优于单纯化疗组,且联合治疗组患者食欲、睡眠、疼痛改善均优于对照组,有统计学意义。因此对于晚期失去手术及放化疗时机的恶性肿瘤患者,CIK治疗疗效显著且不良反应轻,值得临床推广及应用。
机构地区 武汉紫荆医院
出处 《绿色科技》 2017年第8期226-228,共3页 Journal of Green Science and Technology
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