螺吡喃嵌段共聚物的荧光性能研究

Study on the Fluorescence Property of Spiropyran-Based Block Copolymer

使用原子转移活性自由基聚合(ATRP)的方法合成了一种含有螺吡喃功能小分子的嵌段共聚物mPEG-PCL-SPMA,通过核磁对该嵌段聚合物的结构进行了表征。在极性溶剂中嵌段共聚物的螺吡喃分子处于空间限域的胶束核中,因而相较于溶液中的螺吡喃小分子其荧光性能得到显著提升。因此,该螺吡喃嵌段共聚物可以在生物成像、荧光标记等方面有潜在的应用价值。

In this study, spiropyran- based copolymer was synthesized via atom transfer radical polymerization （ATRP） and thestructure of mPEG - PCL - SPMA was characterized by 1HNMR. The spiropyran species of spiropyran - based eopolymer isembedded in cores of the micelles which produce effects of conformational constraint in polar solution. The fluorescence propertyof the encapsulated spiropyran differ dramatically from those of the same species in solution, making micelles - protectedspiropyran attractive materials for more potential applications such as fluorescence imaging and biological fluorescent labeling.