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Clinical outcomes at one year following keratoconus treatment with accelerated transepithelial cross-linking

Clinical outcomes at one year following keratoconus treatment with accelerated transepithelial cross-linking
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摘要 This study evaluated the clinical outcomes in keratoconus corneas following accelerated transepithelial corneal collagen cross-linking(CXL)(Avedro KXL system,Waltham,MA,USA) over one year of follow-up.The mean depth of the demarcation line measured by optical coherence tomography(OCT) was 205.19 μm.One month after surgery,a non-statistically significant change was noted in sphere(P= 0.18) and in spherical equivalent(P= 0.17),whereas a significant improvement was observed in corrected distance visual acuity(P=0.04).A significant change was observed in topographic astigmatism(P= 0.03) and posterior corneal a sphericity(P= 0.04).Accelerated transepithelial CXL may be a useful technique for the management of progressive keratoconus. This study evaluated the clinical outcomes in keratoconus corneas following accelerated transepithelial corneal collagen cross-linking(CXL)(Avedro KXL system,Waltham,MA,USA) over one year of follow-up.The mean depth of the demarcation line measured by optical coherence tomography(OCT) was 205.19 μm.One month after surgery,a non-statistically significant change was noted in sphere(P= 0.18) and in spherical equivalent(P= 0.17),whereas a significant improvement was observed in corrected distance visual acuity(P=0.04).A significant change was observed in topographic astigmatism(P= 0.03) and posterior corneal a sphericity(P= 0.04).Accelerated transepithelial CXL may be a useful technique for the management of progressive keratoconus.
出处 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2017年第4期652-655,共4页 国际眼科杂志(英文版)
关键词 comeal collagen cross-linking KERATOCONUS transepithelial cross-linking accelerated transepithelial cross-linking corneal ectasia comeal collagen cross-linking keratoconus transepithelial cross-linking accelerated transepithelial cross-linking corneal ectasia
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