中医辨证施治抑制肠息肉术后复发32例临床研究

Clinical effect of TCM syndrome differentiation-based treatment in inhibiting postoperative recurrence of large intestinal polyp:a report of 32 cases

目的:探讨中医辨证施治抑制大肠息肉术后复发的效果。方法:将65例大肠息肉患者随机分为治疗组32例和对照组33例。对照组在内镜下行息肉切除术后予以西医常规对症支持治疗,治疗组在对照组治疗基础上依证型辨证治疗,连续服用中药3个月,1年后随访复查肠镜。结果:Logistic回归分析得出,年龄、息肉大小、数量、病理类型、治疗方式是影响大肠息肉术后复发的危险因素;两组中医症状评分治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P<0.05);术后复发率治疗组为12.5%,对照组为30.3%,组间比较,差异有统计学意义(P<0.05)。结论:辨证分型干预可以有效降低大肠息肉切除术后复发率。

Objective：To investigate the clinical effect of traditional Chinese medicine （TCM） syndrome differen- tiation - based treatment in inhibiting postoperative recurrence of large intestinal polyp. Methods ： A total of 65 patients with large intestinal polyp were randomly divided into treatment group （n =32） and control group （n =33）. The con- trol group was treated with endoscopic polypectomy,followed by symptomatic and supportive Western medicine treat- ment, while the treatment group was given TCM syndrome differentiation - based treatment for three months in addition to the treatment for the control group. These patients were re - examined by colonoscopy one year later. Results ： Logis- tic regression analysis showed that age, the size and number of polyps, pathological type, and treatment method were risk factors for postoperative recurrence of large intestinal polyp. The TCM syndrome score showed significant differ- ences within the same group before and after treatment and between the two groups after treatment （P 〈 0. 05 ）. The postoperative recurrence rate was significantly lower in the treatment group than in the control group （12. 5% vs 30. 3 %, P 〈 0. 05）. Conclusion： Intervention based on TCM syndrome type can effectively reduce the postoperative re- currence rate of large intestinal polyp.