超声造影在卵巢肿块诊断中的应用价值

Application of Contrast-enhanced Ultrasound in the Diagnosis of Ovarian Masses

目的探讨超声造影在卵巢肿块诊断中的应用价值。方法对常规超声检查发现卵巢肿块但性质难以鉴别的患者94例行超声造影检查并绘制时间-强度曲线(TIC),分析比较不同肿块的造影剂灌注特点及TIC参数的差异。结果卵巢肿块的超声造影灌注特点及TIC参数存在差异。良性组的AT、TTP晚于恶性组,PI低于恶性组,差异有统计学意义(P<0.05);良性肿瘤组的AT、TTP晚于恶性组,PI低于恶性组,差异有统计学意义(P<0.05);非肿瘤性病变组的TTP晚于恶性组,PI低于恶性组,差异有统计学意义(P<0.05);非肿瘤性病变组的AT早于良性肿瘤组,差异有统计学意义(P<0.05)。结论不同性质的卵巢肿块的超声造影灌注特点及TIC参数不同,超声造影有助于卵巢良恶性肿块的诊断及鉴别诊断。特别是对常规超声表现复杂、难以定性的卵巢肿块,超声造影同样具有重要的临床应用价值。

Objective To investigate the application value of contrast - enhanced ultrasound in the diagnosis of ovarian masses. Methods Ninety - four patients with ovarian masses were observed and undetermined by conventional ultrasound examinations who were underwent contrast - enhanced ultrasound examinations and were made the time - intensity curve. By analyzing the perfusion characteristics and the quantitative parameters of time - intensity curve, we compared the difference of different masses. Results The perfusion characteristics and the quantitative parameters of the time - intensity curve were different. The arrival time and the time to peak intensity of be- nign masses were later than those of malignant tumors. The peak iniensity of benign masses was lower than that of malignant tumors. There was a significant difference between the two groups. The arrival time and the time to peak intensity of benign tumors were later than those of malignant tumors. The peak intensity of benign tumors was lower than that of malignant tumors. There was a significant difference be- tween the two groups. The time to peak intensity of non - tumorous lesions was later than that of malignant tumors. The peak intensity of nontumorous lesions was lower than that of malignant tumors. There was a significant difference between the two groups. The arrival time of non - tumorous lesions was earlier than that of benign tumors. There was a significant difference between the two groups. Conclusion The perfusion characteristics and the quantitative parameters that draw from the time - intensity curve of different masses are different. Contrast - enhanced ultrasound is contributive to the diagnosis and the differential diagnosis of different masses. Contrast - enhanced ultrasound also has great clinical values to those ovarian masses whose uhrasonic appearance is complex and difficult to diagnose qualitatively.