2015年新疆疑似预防接种异常反应信息管理系统数据分析

Analysis of data of adverse events from immunization information management system in Xinjiang, 2015

目的分析2015年新疆疑似预防接种异常反应(AEFI)发生特征,评价疑似预防接种异常反应信息管理系统运转情况。方法通过疑似预防接种异常反应信息管理系统,收集截止2015年12月31日新疆报告的疑似预防接种异常反应个案,采用描述性方法进行流行病学分析。结果 2015年报告2 705例疑似预防接种异常反应病例中,一般反应2 696例、占99.67%,异常反应2例、占0.07%,偶合症6例、占0.22%,不明原因1例、占0.04%,无心因性反应和接种事故等发生;非严重疑似预防接种异常反应2 698例、占99.74%,严重疑似预防接种异常反应7例、占0.26%;其中男性1 480例、占54.71%,女性1 225例、占45.29%;1岁及以下组503例、占18.59%,2~6岁组1 924例、占71.13%,7岁及以上组278例、占10.28%,各年龄组差异无统计学意义(χ~2=1.001,P>0.05);第一季度病例最少(623例)、占23.03%,第二和第三季度病例较多(713例和711例)、均占26.28%,各季度差异无统计学意义(χ~2=4.014,P>0.05)。结论 2015年全疆疑似预防接种异常反应监测的敏感性较2014年有较大提高,但各地区报告差异较大;新疆预防接种异常反应估算报告发生率均在预期发生范围内。

Objective To evaluate data from Adverse Events Following Immunization Information Management System （AEFI IMS） in Xinjiang, to assess the operation status ofAEFI IMS. Methods AEFI data from AEFI IMS prior to Decem- ber 31, 2015, were collected and analyzed with descriptive statistics. Results In 2015, out of 2 705 reported suspicious cas- es with AEFI, there were 2 696 cases with general reaction, accounting for 99.67%; 2 cases with abnormal reaction, account- ing for 0.07%; 6 cases with coincidence, accounting for 0.22%; and 1 case with unknown causes, accounting for 0.04%. No psychogenic reaction, and inoculation accident etc. occurred. There were 2 698 cases with no-severe suspicious abnormal re- action, accounting for 99.74%, and 7 cases with severe suspicious abnormal reaction, accounting for 0.26%, including 1 480 cases of the male （54.71%）, 1 225 cases of the female （45.29%）. The reported cases were most of the children under 6 year-old, including 503 cases less than 1 year-old （18.59%）, 1 924 cases from 2 to 6 year-old （71.13%）, 278 cases over 7 year-old （10.28%）, and no statistical difference was found among age groups （χ^2=l.001, P〉0.05）. The cases were the least （623 cases） in the first quarter （23.03%）, then in the second and third quarter （713 cases and 711 cases, accounting for 26.28%, respectively）, without statistical difference （Z2=4.014, P〉0.05）. Conclusions The surveillance sensitivity of suspi- cious AEFI in Xinjiang is significantly higher in 2015 than in 2014. Regional reports vary greatly. The incidence of adverse re- actions in Xinjiang is estimated to be within the expected range.