儿童孤独症谱系障碍环境危险因素研究进展

Research progress of environmental risk factors of children's autism spectrum disorder

孤独症谱系障碍(ASD)是一组以社会交往和交流障碍、兴趣狭窄和重复刻板性行为为主要特征的神经发育障碍性疾病。本文针对ASD环境危险因素的研究进行综述,包括直接环境因素如母孕期疾病史、异常史、用药史,儿童出生异常情况;间接环境因素如家庭环境、生活环境及生后养育史等,以了解出生前、围产期及出生后环境因素对ASD发病的影响,为更好的理解、预防和早期干预ASD开辟新思路。

Autism spectrum disorder （ASD） is a group of neurodevelopmental disorders defined by social and commu- nication deficits, narrow interesting and repetitive behaviors. This article summarized the studies of environmental risk fac- tors for ASD,including direct environmental factors as disease, abnormal and medication during pregnancy, children born ab- normal ; indirect environmental factors as family environment, living environment and history of postnatal nurture,as to know the influence of the risk factors during prenatal,perinatal and after birth,to break a new path to better understand, prevent and early intervene the ASD.