阿法骨化醇治疗寻常性痤疮64例临床观察

Afar Calciferol in Treatment of Common Acne,64 Cases of Clinical Observation

目的评价补充维生素D在治疗寻常性痤疮中的作用。方法将入选的126例痤疮患者采用随机数字表法分为两组,全部患者予维胺酯胶囊50mg(3次/d)和罗红霉素0.15g(2次/d)口服,治疗组(64例)同时每天予阿法骨化醇软胶囊0.5μg口服,疗程均为4周。结果治疗组有效率82.81%;对照组有效率48.39%,差异有统计学意义(P<0.05)。另外,治疗过程中两组患者均未见严重的不良反应。结论补充维生素D对治疗寻常性痤疮有显著的提高疗效作用。

Objective To evaluate vitamin D supplements in the treatment of common acne.Methods Selected 126 patients with acne is divided into two groups by random number table method, all patients to d amine ester capsule 50 mg（three times/d）and 0.15 g（2 times/d）oral erythromycin, the treatment group（64 cases）and at the same time every day to afar calciferol 0.5 ug soft capsule oral, a course of 4 weeks.Results The treatment group effective rate was 82.81%.The control effectiveness 48.39%, the difference was statistically significant（P〈 0.05）.In addition, the treatment process of two groups of patients were not seen obvious adverse reactions.Conclusion Vitamin D supplement to the treatment of common acne has significantly improve curative effect.