白细胞过滤对输血反应的临床意义

Clinical Significance of Leukocyte Filtration on Transfusion Reaction

目的:分析白细胞过滤对输血反应的临床意义。方法:随机选取我院收治需要输血治疗的患者,共50例,收治时间在2015年3月~2015年9月之间,并将其分为2组,研究组患者进行白细胞过滤,对照组则不予以白细胞过滤,比较2组患者的输血后反应发生率、输血后凝血酶原时间(PT)和活化部分凝血酶原时间(APTT)的变化情况。结果:与对照组相比,研究组患者的输血后反应发生率明显降低,数据差异有统计学意义,p<0.05;与对照组相比,研究组患者的PT和APTT明显减少,差异显著,有统计学意义,p<0.05。结论:在输血治疗后,应给予白细胞过滤,可以有效降低患者的输血后反应发生率,缩短PT和APTT,以此保证输血治疗的临床安全性。

Objective： To analyze the clinical significance of leukocyte filtration on transfusion reaction. Methods： Totally, 50 patients needing blood transfusion were admitted and treated in our hospital from March 2015 to September 2015 as the objects of study. They were randomly divided into test group and control group. Patients in test group were treated with leukocyte filtration, while patients in control group did not be. After transfusion, the changes between two groups were compared, including prothrombin time （PT）, activated partial thromboplastin time （APTT）, and incidence of transfusion reactions. Results： Comparing with control group, the incidence of post-transfusion reaction, prothrombin time, and activated partial thromboplastin time were significantly lower in test group （p 〈 0.05）. Conclusions： The leukocyte should be filtrated after transfusion can reduce the incidence of transfusion reactions, prothrombin time, and activated partial thromboplastin time, in order to ensure the transfusion safety.