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ENA抗体联合检测血清免疫球蛋白、补体在SLE诊断中的价值研究 被引量:7

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摘要 目的探析ENA抗体联合检测血清免疫球蛋白、补体在系统性红斑狼疮(SLE)诊断中的应用价值。方法将2015年1月~2016年4月确诊的45例SLE患者作为研究组,对照组为27例健康受试者,两组受试者均于晨间空腹采血,检测ENA抗体、抗ds-DNA、C3、C4、IgM、IgA、IgG。结果研究组的IgM、IgA、IgG水平均比对照组高,差异有统计学意义(P<0.05)。研究组的C3、C4比对照组低,差异有统计学意义(P<0.05)。对照组存在1例IgG与1例C3呈阳性,其他项目的检查结果均不存在阳性。研究组病例中自身抗体与血清免疫呈阳性,其中抗Sm阳性率为31.11%,抗ds-DNA阳性率为37.78%,C3的阳性率为68.89%,C4的阳性率为64.44%,两组差异具有统计学意义(P<0.05)。结论 ENA抗体与体液免疫检验在SLE诊断中具有较高的应用价值,将两者联合使用,可为临床SLE的诊治及预后评价提供借鉴。
机构地区 湘潭县人民医院
出处 《中国处方药》 2017年第5期132-133,共2页 Journal of China Prescription Drug
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