利凡诺联合米非司酮在二次瘢痕子宫妊娠中晚期引产中的效果观察

Observation on the effect of rivanol combined with mifepristone on induction of labor in the advanced pregnancy of secondary scar uterus

目的观察利凡诺联合米非司酮在二次瘢痕子宫中晚期妊娠引产的应用效果。方法选择本院治疗的二次瘢痕子宫中晚期孕妇46例,随机分为米非司酮+利凡诺组(观察组)和利凡诺组(对照组)各23例,观察组孕妇采用米非司酮联合利凡诺羊膜腔注射引产,对照组孕妇采用单独利凡诺进行引产。评价两组孕妇的引产结局和不良反应的发生率。结果观察组产妇的宫缩至分娩时间及总产程时间均明显短于对照组(P<0.05),产后出血量亦少于对照组(P<0.05)。观察组产妇产道损伤、产道感染发生率低于对照组(P<0.05)。结论利凡诺联合米非司酮在二次瘢痕子宫中晚期妊娠引产中具有良好效果、并发症少,可作为二次瘢痕子宫妊娠引产的一种方法。

Objective To observe the application effect of rivanol combined with mifepristone in the induction of labor in the advanced pregnancy of secondary scar uterus. Methods Forty-six patients with advanced pregnancy in the sec- ondary sear uterus were randomly divided into the mifepristonc＋rivanol group （observation group） and the rivanol group （control group）, with 23 cases in each group. The observation group was treated with mifepristone combined with rivanol in amniotic injection for induction of labor, and the control group of pregnant women was given rivanol alone to induce labor. The incidences of induction outcome and adverse events between the two groups of pregnant women were evalu- ated. Results The uterine contractions and the time of delivery in the observation group were significantly shorter than those in the control group（P〈0.05）. The postpartum hemorrhage was also lower than that of the control group（P〈0.05）. The incidences of birth canal injury and birth canal infection in the observation group were lower than those in the control group（P〈0.05）. Conclusion Rivanol combined with mifepristone has a good effect and less adverse reaction in the induction of advanced pregnancy with the secondary scar uterus, which can be used as a method for the induction of labor in secondary scar pregnancy.