右美托咪啶对全麻患者术后导尿管所致躁动的影响

Preventive effects of dexmedetomidine on restlessness in patients with indwelling urinary catheter following general anesthesia

目的:探讨右美托咪啶(DEX)对全麻患者术中插导尿管导致术后躁动的预防作用。方法:选择行择期胃癌全麻手术患者92例,ASAⅠ~Ⅱ级,按随机数字表法将其分为A组和B组,每组46例。手术结束前30 min A组DEX(0.4μg/kg)15min泵入,B组相同量生理盐水15 min泵入。对两组患者的苏醒时间、拔管时间和拔管血压进行观察,并且对患者处于苏醒期的躁动情况进行评级。结果:手术结束后,两组患者的苏醒时间、拔管时间和拔管血压有统计学意义(P<0.05),躁动发生率A组比B组明显降低(P<0.05)。结论:DEX可有效预防全麻患者术中留置导尿管术后躁动的发生。

Objective：To observe the effects of dexmedetomidine （DEX） in preventing postoperative restlessness in patients with indwelling urinary catheter following general anesthesia.Methods：Ninety-two ASA I-II patients with gastric cancer,undergone elective surgery by general anesthesia in our hospital were included and equally randomized into group A and group B as random digital table.Dexmedetomidine was administered with micro-infusion pump in dose of 0.4 μg / kg in patients in group A 15 min before procedure completion,and normal saline was used in group B in the same dose and protocol as group A.The awakening time,extubation time and extubation blood pressure were observed,and the restlessness of the patients in the recovery period was evaluated.Results：At the end of the operation,the awakening time,extubation time and extubation blood pressure of the two groups were statistically significant （P〈0.05）,while the incidence of restlessness was significantly lower in group A than in group B （P〈0.05）.Conclusion：Dexmedetomidine can effectively prevent the occurrence of restlessness in patients with indwelling urinary catheter following general anesthesia.