甲状腺癌术中应用纳米碳示踪剂对甲状旁腺的保护作用

Protective effect of nano carbon tracer on parathyroid function in the surgery of thyroid cancer

法将浙江省金华市浦江县人民医院2014年6月至2016年3月178例甲状腺癌患者按照随机数字表法分为对照组与观察组，各89例。其中对照组实施常规手术，观察组于手术期间应用于纳米碳混悬液。检测2组术后3 d时血甲状旁腺激素、血钙水平，同时统计2组低甲状旁腺激素、正常甲状旁腺激素及低钙患者人数。 结果观察组术后血钙水平正常率91.01%（81/89），明显高于对照组67.42%（60/89）（P〈0.05）,观察组术后甲状旁腺激素正常率94.38%（84/89），明显高于对照组64.04%（57/89）（P〈0.05）。 结论甲状腺癌术中应用纳米碳示踪剂对甲状旁腺具有较好的保护作用。

To investigate the effect of nano carbon tracer for protecting parathyroid function in the surgery of thyroid cancer.MethodsA total of 178 patients with thyroid cancer admitted in our hospital from Jun. 2014 to Mar. 2016 were collected and divided into the control group and the observation group according to the random number table method, 89 cases in each group. The control group received routine surgery, while the observation group received nanocarbon suspension during surgery. The levels of serum parathyroid hormone and serum calcium in the 2 groups were measured at 3 days after surgery, and the patients with low parathyroid hormone, normal parathyroid hormone and low calcium were counted.ResultsThe rate of ormal serum calcium in the observation group was 91.01% （81/89） , significantly higher than 67.42% （60/89） in the control group （P〈0.05） . The rate of normal parathyroid hormone in observation group was 94.38% （84/89） , significantly higher than 64.04% （57/89） in the control group （P〈0.05） .ConclusionThe nano carbon tracer is helpful for protection of parathyroid function in the surgery of thyroid cancer.