射频微等离子体联合局部电子束治疗瘢痕疙瘩的临床效果

Clinical efficacy of micro-plasma radiofrequency combined with local electron-beam radiation therapy in treatment of keloids

目的 探讨射频微等离子体技术联合局部电子束放射治疗瘢痕疙瘩的临床效果.方法 入组瘢痕疙瘩半年以上患者15例,经单次射频微等离子体治疗,治疗功率80～100W,滑动模式.治疗后24 h内及治疗后1周行大分割电子束照射,照射剂量9 Gy/次,照射范围为瘢痕外1 cm.分别于治疗前及治疗后半年进行温哥华瘢痕量表（VSS）评估和患者满意度评价,同时记录不良反应.结果 15例患者VSS评分术前（11.73±1.12）分,术后（3.87±2.53）分（P＜0.05）.其中痊愈1例,显效10例,好转3例,无效1例.患者评价：非常满意6例,满意6例,基本满意2例,不满意1例.不良反应：1例出现放疗区皮肤色素沉着（前胸部）,1例出现延迟愈合.结论 射频微等离子体联合局部电子束放射治疗瘢痕疙瘩安全、有效,具有较好的临床应用价值.

Objective To study the clinical efficacy of micro-plasma radiofrequency with joint electron-beam radiation treatment for keloids.Methods A total of 15 patients with keloids over half a year were treated with single time micro-plasma radiofrequency technology by roller tip at 80-100 watts.The hypofractionated electron-beam was used,with 9 Gy dose per time covering the scar with a 1 cm margin,within 24 hours and 1 week after the micro-plasma treatment.The Vancouver Scar Scales （VSS） were assessed before and 6 months after the treatment.Patients＇ satisfaction and the adverse reactions were evaluated 6 months after the treatment.Results There was astatistically significant difference between the mean VSS of 15 patients pre-and 6 months posttreatment （from 11.73± 1.12 to 3.87±2.53,P〈0.05）.The degree of improvement was：excellent in 1 case,good 10 cases,fair 3 cases,and poor 1 case.Patients＇ assessment was：extremely satisfied in 6 cases,satisfied 6 cases,approximately satisfied 2 cases and dissatisfied 1 case.The adverse reactions included hyperpigmentation within the radiation field on the anterior chest wall in 1 case and delayed healing of 1 patient ＇s scar wound.Conclusions Micro-plasma radiofrequency combined with electron-beam radiation therapy is highly effective and safe on keloids with good clinical application value.