摘要
A method was developed on a gas chromatograph coupled to a triple quadrupole mass spectrometer(GC-MS/MS) for trace level determination of polychlorinated dibenzo-p-dioxins/dibenzofurans(PCDD/Fs) and dioxin-like polychlorinated biphenyls(DL-PCBs) in food and feed. The results demonstrated good sensitivity and repeatability for PCDD/Fs and DL-PCBs at an extremely low level(10 pg mL^(-1) for 2,3,7,8-TCDD/F), as well as wide linear response of over 3 or 4 orders of magnitude in concentration ranges; 0.5–200 ng mL^(-1) for PeCDD/F and 0.2–2000 ng mL^(-1) for DL-PCBs. The method detection limits for PCDD/Fs and DL-PCBs were in the range from 0.018–0.17 pg g^(-1) to 0.13–0.36 pg g^(-1), respectively. The performance of the GC-MS/MS for food and feed sample analysis showed high precision and accuracy compared to the high resolution gas chromatograph/high resolution mass spectrometer. The results indicated the feasibility of GC-MS/MS as a confirmatory method for the measurement of PCDD/Fs and DL-PCBs in food and feed as required by European Union legislation.
A method was developed on a gas chromatograph coupled to a triple quadrupole mass spectrometer （GC-MS/MS） for trace level determination of polychlorinated dibenzo-p-dioxins/dibenzofurans （PCDD/Fs） and dioxin-like polychlorinated biphenyls （DL-PCBs） in food and feed. The results demonstrated good sensitivity and repeatability for PCDD/Fs and DL-PCBs at an extremely low level （10 pg mL-1 for 2,3,7,8-TCDD/F）, as well as wide linear response of over 3 or 4 orders of magnitude in concentration ranges; 0.5-200 ng mL^-1 for PeCDD/F and 0.2-2000 ng mL^-1 for DL-PCBs. The method detection limits for PCDD/Fs and DL-PCBs were in the range from 0.018-0.17 pg g^-1 to 0.13-0.36 pg g^-1, respectively. The performance of the GC-MS/MS for food and feed sample analysis showed high precision and accuracy compared to the high resolution gas chromatograph/high resolution mass spectrometer. The results indicated the feasibility of GC-MS/MS as a confirmatory method for the measurement of PCDD/Fs and DL-PCBs in food and feed as required by European Union legislation.
基金
supported by the National Natural Science Foundation of China(21477156,21477155,41276195)
Chinese Academy of Sciences(XDB14010100)
the National Basic Research Program of China(2015CB453101)
