VSD技术结合中药消炎膏、生肌膏治疗四肢开放性、感染性骨折的临床研究

Clinical study on VSD technique combined with traditional Chinese medicine antiphlogistic ointment and Shengji ointment in the treatment of open and infectious fractures of extremities

目的探讨应用负压封闭引流技术(VSD)结合中药消炎膏、生肌膏治疗四肢开放性、感染性骨折的临床疗效和意义。方法 90例四肢开放性、感染性骨折患者,随机分为观察组和对照组,各45例。观察组应用VSD技术结合中药消炎膏、生肌膏治疗,对照组单独应用VSD技术治疗。比较两组患者治疗效果、手术指标(使用VSD次数、平均恢复时间、肉芽组织生长时间、上皮组织生长时间)、二次手术率及平均住院费用等。结果观察组优良率88.89%高于对照组的71.11%;观察组使用VSD次数(51±11)明显少于对照组(73±15)次;观察组患者二次手术率26.67%明显低于对照组的77.78%;观察组平均恢复时间、肉芽组织生长时间、上皮组织生长时间分别为(16.5±3.6)、(4.8±2.3)、(6.7±3.4)d,短于对照组的(23.2±3.9)、(12.6±2.5)、(12.7±4.6)d;观察组患者平均住院费用(8374.2±765.2)元明显低于对照组的(14596.6±2341.5)元;差异均具有统计学意义(P<0.05)。结论 VSD技术结合中药消炎膏、生肌膏治疗四肢开放性、感染性骨折临床疗效肯定,此疗法可以明显缩短疗程,降低治疗费用,减轻社会和家庭的经济负担,具有良好的社会效益,值得基层医院推广应用。

Objective To explore the clinical curative effect and significance of vacuum sealing drainage（VSD） technique combined with traditional Chinese medicine antiphlogistic ointment and Shengji ointment in the treatment of open and infectious fractures of extremities. Methods A total of 90 patients with open and infectious fractures of extremities were randomly divided into observation group and control group, with 45 cases in each group. The observation group received VSD technique combined with traditional Chinese medicine antiphlogistic ointment and Shengji ointment for treatment, and the control group received VSD technique only for treatment. Comparison were made on treatment effect, operation indicators（VSD using times, average recovery time, granulation tissue growth time, epithelial tissue growth time）, secondary surgery rate and average hospitalization costs in two groups. Results The observation group had higher excellence-good rate as 88.89% than 71.11% in the control group; the observation group had obviously less VSD using times as（51±11） times than（73±15） times in the control group; the observation group had obviously lower secondary surgery rate as 26.67% than 77.78% in the control group; the observation group had average recovery time, granulation tissue growth time, epithelial tissue growth time respectively as（16.5±3.6）,（4.8±2.3）and（6.7±3.4） d, which were lower than（23.2±3.9）,（12.6±2.5） and（12.7±4.6） d in the control group; the observation group had obviously lower average hospitalization costs as（8374.2±765.2） yuan than（14596.6±2341.5） yuan in the control group. All their difference had statistical significance（P〈0.05）. Conclusion Combination of VSD technique and traditional Chinese medicine antiphlogistic ointment, Shengji ointment shows affirmative curative effect in the treatment of open and infectious fractures of extremities, which can obviously shorten treatment course, reduce treatment costs, ease economic burden of society and family, and it has good social efficiency. So it is worth wide popularization and application in basic-level hospitals.