钼靶引导下立体定位空心针活检在乳腺钙化灶疾病诊断中的应用

Application of molybdenum target-guided stereotactic core needle biopsy in diagnosis of breast calcification disease

目的分析和探讨乳腺钙化灶疾病诊断应用钼靶引导下立体定位空心针活检的方法与效果。方法 96例接受活检的乳腺钙化灶疾病患者,分别行常规X线引导下经皮穿刺导丝定位手术活检、钼靶引导下立体定位空心针活检。对两种活检方法的恶性病变检出率进行计算和对比,并观察立体定位空心针活检结果。结果钼靶引导下立体定位空心针活检恶性病变检出率为55.21%,显著高于常规X线引导下经皮穿刺导丝定位手术活检的30.21%,差异具有统计学意义(P<0.05)。经钼靶引导下立体定位空心针活检,结果显示,96例患者以导管原位癌最多,占37.50%(36/96)。结论钼靶引导下立体定位空心针活检恶性病变检出率较高,且与常规X线引导下经皮穿刺导丝定位手术活检比较,其还具有不影响美观、微创的优势,值得推广应用。

Objective To analyze and investigate measure and effect by molybdenum target-guided stereotactic core needle biopsy applied in diagnosis of breast calcification disease. Methods A total of 96 patients with breast calcification disease received respectively conventional X-ray-guided percutaneous puncture wire localization surgical biopsy and molybdenum target-guided stereotactic core needle biopsy. Detection rate of malignant lesion was calculated and compared between the two measures, and observation was made on biopsy outcomes by stereotactic core needle biopsy. Results Molybdenum target-guided stereotactic core needle biopsy had detection rate of malignant lesion as 55.21%, which was obviously higher than 30.21% by conventional X-ray-guided percutaneous puncture wire localization surgical biopsy, and the difference had statistical significance（P0.05）. Molybdenum target-guided stereotactic core needle biopsy showed the most common lesion as ductal carcinoma in situ in 96%, accounting for 37.50%（36/39）. Conclusion Molybdenum target-guided stereotactic core needle biopsy shows high detection rate of malignant lesion. Comparing with conventional X-rayguided percutaneous puncture wire localization surgical biopsy, this method contains advantages of unaffected appearance and small invasion. It is worth promoting and applying.