苦豆子药材中生物碱提取工艺优化

Optimization on Extraction Technology of Sophora alopecuroides

目的:建立优化的苦豆子药材超声提取工艺。方法:以吸光度为指标,采用正交试验设计的方法,考察料液比、乙醇浓度、超声时间、粉碎度对苦豆子药材提取的影响,以确定最佳提取工艺。结果:各因素对提取率的影响主次顺序为D>B>C>A,优化的苦豆子提取工艺为65%乙醇,料液比1∶5,提取时间2h,粒度60目。结论:该研究建立的优化的苦豆子药材提取工艺稳定可行。

Objective： To establish an optimized beans bitter herbs Ultrasonic Extraction Process. Methods： Absorbance as an index, the method of orthogonal experimental design to investigate solid-liquid ratio, ethanol concentration, ultrasonic time, the impact of grinding degree of extracted to determine the optimum extraction process. Results ： The primary and secondary order of each factor＇s influence on the extraction yield D〉 B 〉 C 〉 A, the best extraction process of 65% ethanol, solid-liquid ratio 1 ： 5, extracting time 2 h, granularity 60 mesh. Conclusion： Optimized beans bitter herbs extraction process is stable.