远隔效应的研究进展与临床意义

Research Progress and Clinical Significance of Abscopal Effect of Radiotherapy

放射治疗作为肿瘤主要的治疗手段之一,近年来得到了长足的发展。随着放疗技术的不断进步和应用,局部放疗激发远隔效应的现象逐渐进入人们的视线。本文将总结肿瘤局部放疗以及联合免疫治疗激发远隔效应的机制和临床研究,阐述局部放疗联合免疫治疗在晚期肿瘤治疗中的重要意义。

Radiotherapy,as one of the main cancer therapies,has made a considerable progress.With the development of radiation technology,the abscopal effect induced by local radiotherapy has been gradually recognized. This article will summarize the mechanisms of abscopal effect after local radiotherapy or combination with immune therapy and related clinical researches,to elaborate its application in the treatment of advanced or metastatic tumors.