肺胃同治法应用于老年慢性阻塞性肺疾病临床治疗中效果分析

Analysis of effect by lung and stomach concurrent therapy applied in clinical treatment of senile chronic obstructive pulmonary disease

目的肺胃同治法应用于老年慢性阻塞性肺疾病(COPD)临床治疗中的效果。方法 50例老年COPD患者,随机分为研究组和对照组,各25例。研究组采用肺胃同治法,给予二陈汤+厚朴麻黄汤进行治疗,对照组采用西医常规治疗,包括异丙托溴铵气雾剂、沙丁胺醇气雾剂、茶碱类及营养支持等。比较两组治疗效果。结果治疗前,两组患者中医证候积分比较差异无统计学意义(P>0.05);治疗后,研究组中医证候积分为(7.75±2.41)分,显著低于对照组的(13.17±1.88)分,差异有统计学意义(P<0.01)。治疗前,两组患者第一秒用力呼气容积(FEV1)、用力肺活量(FVC)比较差异无统计学意义(P>0.05);治疗后,研究组FEV1为(1.28±0.15)L、FVC为(2.37±0.29)L,均明显高于对照组的(0.81±0.22)、(1.85±0.14)L,差异有统计学意义(P<0.01)。结论肺胃同治法应用于老年COPD临床治疗中,可有效提升患者临床疗效,改善肺功能,缓解肺功能长期下降趋势,值得临床推广应用。

Objective To analyze effect by lung and stomach concurrent therapy applied in clinical treatment of senile chronic obstructive pulmonary disease（COPD）. Methods A total of 50 senile COPD patients were randomly divided into research group and control group, with 25 cases in each group. The research group received lung and stomach concurrent therapy by Erchen decoction ＋ Houpu Mahuang decoction, and the control group received conventional Western therapy by ipratropium bromide aerosol, salbutamol aerosol, theophylline and nutrition support. Curative effects were compared between the two groups. Results Before treatment, there was no statistically significant difference of traditional Chinese medicine syndrome score between the two groups（P〉0.05）. After treatment, the research group had obviously lower traditional Chinese medicine syndrome score as（7.75±2.41） points than（13.17±1.88） points in the control group, and their difference had statistical significance（P〈0.01）. Before treatment, the difference of forced expiratory volume in 1 second（FEV1） and forced vital capacity（FVC） had no statistical significance between the two groups（P〉0.05）. After treatment, the research group had FEV1 as（1.28±0.15） L and FVC as（2.37±0.29） L, which were all higher than（0.81±0.22） and（1.85±0.14） L in the control group, and their difference had statistical significance（P〈0.01）. Conclusion Implement of lung and stomach concurrent therapy in the clinical treatment of senile COPD can effectively enhance clinical effect for patients, improve pulmonary function and relieve long-term downtrend of their pulmonary function. It is worth clinical promotion and application.