星状神经节脉冲射频治疗顽固性功能性便秘的疗效

Effect of stellate ganglion pulsed radiofrequency in the treatment of intractable functional constipation

目的探讨星状神经节脉冲射频治疗顽固性功能性便秘的疗效。方法顽固性功能性便秘患者88例，随机分为A、B两组，每组44例，A、B两组均在润肠药、肠动力药等基础上分别行星状神经节脉冲射频和星状神经节阻滞治疗，A组先行一侧星状神经节脉冲射频治疗，24h后行另一侧治疗；B组星状神经节阻滞每日1次，两侧交替，20次为1个疗程。于1个疗程结束后当日、3个月、6个月时评价两组症状积分、疗效及并发症。结果两组治疗后各症状积分较治疗前降低（P〈0．05），但A组症状积分降低（5．0±1．3）较B组（8．6±2．5）更明显（P〈0．05）；治疗结束后当日，A组和B组总有效率分别为90．1％，79．5％，A组疗效优于B组（P〈0．05）；治疗后3个月和6个月时两组疗效差异更显著（P〈0．05），A组疗效更持久，穿刺次数显著减少，并发症更少。结论星状神经节脉冲射频治疗顽固性功能性便秘安全有效。

Objective To explore the effect of stellate ganglion pulsed radiofrequency in the treatment of intractable functional constipation. Methods Eighty-eight patients with intractable functional constipation were randomly divided into group A and group B, 44 cases in each group. On the basis of conventional treatment, the patients in group A received stellate ganglion pulsed radiofrequency, and stellate ganglion block in group B. Stellate ganglion pulsed radiofrequency was performed in one side, and in the other side after 24 hours. Stellate ganglion block was carried out once a day, 20 days for one course at alternate sides. The symptom integrals were evaluated after the treatment. The symptom integrals, effects and complications were assessed at the end of treatment day, and 3,6 months after the treatment. Results The symptom integrals were lower after the treatment as compared with those before the treatment （P〈 0.05） , which was more obvious in group A （P〈 0.05）. The total effective rate was 90.1% and 79.5% in group A and group B at the day after the treatment respectively （P 〈 0.05）, with more significant difference at 3 and 6 months after the treatment. The times of puncture and the complications were greatly reduced in group A. Conclusion Stellate ganglion pulsed radiofrequency is safe and effective in the treatment of intractable functional constipation.