针灸联合中药灌肠治疗慢性盆腔炎临床疗效Meta分析

Clinical Effect of Acupuncture and Moxibustion Combined with Traditional Chinese Medicine Enema in the Treatment of Patients with Chronic Pelvic Inflammatory Disease: A Meta-analysis

目的:系统评价针灸联合中药灌肠治疗慢性盆腔炎临床疗效。方法:检索中国期刊全文数据库、万方数据库、中国科技期刊全文数据库、Pub Med、EMbase数据库从建库到2016年2月发表的关于针灸联合中药灌肠治疗慢性盆腔炎的文献,并采用系统评价和Meta分析方法进行分析。结果:本研究最终纳入随机对照试验12项共942例慢性盆腔炎患者。Meta分析显示,针灸联合中药灌肠治疗慢性盆腔炎的总有效率[合并比值比(odds ratio,OR)=6.32,95%可信区间(confidence interval,CI):3.96~10.08,P<0.00001]、治愈率(合并OR=2.69,95%CI:2.02~3.59,P<0.00001)均优于对照组。结论:针灸联合中药灌肠治疗慢性盆腔炎临床疗效优于单纯中药灌肠治疗,但这一结论尚需更多优质的随机双盲对照实验来进一步证明。

Objective： To comprehensively study the effect of acupuncture and moxibustion combined with traditional Chinese medicine enema in the treatment of patients with chronic pelvic inflammatory disease（CPID）. Methods：Relevant literatures of acupuncture and moxibustion combined with traditional Chinese medicine ene- ma in the treatment of patients with chronic pelvic inflammatory disease were collected from databases of CNKI, VIP,Wanfang,Pubmed and EMbase up to January 2016,and system evaluation and Meta- analysis were performed. Results：A total of 12 randomized controlled trials that met the inclusion criteria were selected for the further analysis. The Meta - analysis results showed that the total effective rate （ combined OR = 6.32,95% CI： 3.96 - 10.08 ,P 〈 0.00001 ） and the curative rate （ combined OR = 2.69,95% CI：2.02 - 3.59 ,P 〈 0. 00001 ） by acupuncture and moxibustion combined with traditional Chinese medicine enema in the treatment of CPID was superior to those by traditional Chinese medicine enema. Conclusion：Acupuncture and moxibustion com- bined with traditional Chinese medicine enema in the treatment of chronic pelvic inflammatory disease has a better efficacy according to the total effective rate and the curative rate. However, large, randomized , double - blind, well -designed controlled trials are warranted to further support this conclusion.