舒芬太尼与瑞芬太尼在急诊脑外伤手术麻醉中应用研究

Sufentanil in Emergency Brain Injury With Fentanyl Anesthesia in Applied Research

目的在急诊脑外伤手术中分别对患者行舒芬太尼、瑞芬太尼麻醉,对比治疗效果。方法选取广州市番禺区钟村医院于2014年8月—2016年4月期间收治的脑外伤患者82例,按照患者入院时间,划分为治疗组与参照组,每组各41例。对参照组患者行瑞芬太尼麻醉,对治疗组患者行舒芬太尼麻醉,对比两组患者的临床治疗效果。结果治疗组患者的麻醉持续时间、苏醒时间、气管插管拔管时间、术后视觉模拟评分法(VAS)评分均明显优于参照组患者,组间差异P<0.05,存在统计学意义,但是两组患者为治疗后的心率(HR)、平均动脉压(MAP)并无显著差异(P>0.05);此外,治疗组患者的不良反应发生率为9.76%,与参照组患者的17.07%对比,组间优势不具有明显性,即P>0.05,不存在统计学意义。结论在急诊脑外伤手术过程中,对患者行舒芬太尼麻醉,不仅可以改善临床麻醉效果,提高临床疗效,保证临床治疗安全,还能促进患者术后恢复,临床应用与推广价值较为显著。

Objective Respectively in emergency brain trauma surgery for patients with sufentanil and fentanyl anesthesia,compare the treatment effect. Methods Will pick in our hospital in August 2014 -April 2016 admitted during the period of 82 patients with traumatic brain injuries, according to the patients in hospital time, divided into treatment group and control group, each group of 41 cases. Line, fentanyl anesthesia in patients with control group,the treatment group patients ShuFen too, anesthesia, compared two groups of patients with the clinical therapeutic effect. Results The treatment group patients duration of anesthesia, wake up of time, trachea cannula extubation time, postoperative visual analogue scale （VAS） score were significantly better than the control group patients, differences between groups （P 〈0. 05, there is statistical significance, but for two groups of patients after treatment of heart rate （HR）, mean arterial pressure （MAP） and there was no significant difference （ P 〉0. 05） ; In addition, the incidence of adverse reactions in patients with treatment group for 9. 76 % , compared with control group patients 17. 07 % , advantages between groups have no obvious sex, namely, P 〉0.05, there is no statistical significance. Conclusion In the process of emergency brain trauma surgery, in patients with ShuFen too, anesthesia, not only can improve clinical anesthesia effect, improve the clinical curative effect, to ensure the safety of clinical treatment, also can promote patients with postoperative recovery, clinical application and popularization value is significant.